Klra2 Antikörper (C-Term)

Produktnummer ABIN6991061

Produktdetails anti-Klra2 Antikörper

Target: Klra2 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 2 (Klra2))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Klra2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Aufreinigung: KLRA2 Antibody is affinity chromatography purified via peptide column.

Immunogen: KLRA2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of mouse KLRA2. The immunogen is located within the last 50 amino acids of KLRA2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KLRA2 antibody can be used for detection of KLRA2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KLRA2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KLRA2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Klra2

Target: Klra2 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 2 (Klra2))

Andere Bezeichnung: KLRA2 (Klra2 Produkte)

Synonyme: Klra30 antikoerper, Ly49b antikoerper, Ly49i6 antikoerper, killer cell lectin-like receptor, subfamily A, member 2 antikoerper, Klra2 antikoerper

Hintergrund: KLRA2 Antibody: KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells. This antibody is predicted to not cross-react with other LY49 receptors.

Gen-ID: 16633

UniProt: Q60660