SMARCAL1 Antikörper

Produktnummer ABIN6972741

Produktdetails anti-SMARCAL1 Antikörper

Target: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Reaktivität: Human, Maus, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMARCAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktmerkmale: SMARCAL1 / HARP (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1, HepA-related protein, DNA-dependent ATPase A) is a member of the SWI / SNF family of ATPases and chromatin remodeling proteins. Unlike other SWI / SNF family members, SMARCAL1 / HARP has not been shown to remodel chromatin, but possesses an ATP-dependent annealing helicase activity. SMARCAL1 reanneals single-stranded DNA bubbles in DNA at DNA replication forks that are bound by Replication Protein A (RPA). Defects in SMARCAL1 / HARP are a cause of Schimke immuno-osseous dysplasia (SIOD) SIOD causes spondyloepiphyseal dysplasia (a disorder of bone growth that results in short stature, skeletal abnormalities, and problems with vision and hearing), renal dysfunction and T-cell immunodeficiency. SMARCAL1 / HARP antibody (mAb) (Clone 4B10) was raised in a Mouse host. It has been validated for use in Immunoprecipitation and Western blot, it has been shown to react with Bovine, Human and Mouse samples.

Aufreinigung: Protein G Chromatography

Immunogen: This SMARCAL1 / HARP antibody was raised against purifed bovine SMARCAL1 / HARP protein.

Klon: 4B10

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu SMARCAL1

Target: SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))

Andere Bezeichnung: SMARCAL1 / HARP (SMARCAL1 Produkte)

Synonyme: SMARCAL1 antikoerper, im:7145331 antikoerper, si:ch211-239d11.1 antikoerper, harp antikoerper, hharp antikoerper, 6030401P21Rik antikoerper, AI851716 antikoerper, Mharp antikoerper, HARP antikoerper, HHARP antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antikoerper, SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antikoerper, Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 L homeolog antikoerper, SMARCAL1 antikoerper, smarcal1 antikoerper, Smarcal1 antikoerper, smarcal1.L antikoerper

Molekulargewicht: 150 kDa

NCBI Accession: NP_788839

Pathways: Embryonic Body Morphogenesis