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GLYR1 Antikörper (C-Term)

GLYR1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6971688
  • Target Alle GLYR1 Antikörper anzeigen
    GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))
    Bindungsspezifität
    • 15
    • 2
    • 1
    • 1
    C-Term
    Reaktivität
    • 29
    • 25
    • 10
    Human
    Wirt
    • 27
    • 2
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GLYR1 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Produktmerkmale
    GLYR1 / NDF (nucleosome-destabilizing factor) that is recruited to gene bodies during transcriptional activation and facilitates Pol II transcription through nucleosomes, where it is proposed to ""unzip"" chromatin during transcription, pushing the polymerase past pause points. It was discovered as a factor that allows p300 to acetylate Histone H3K56, which is normally an inaccessible residue for this modification. GLYR1 is shown to associate with a subset of highly transcribed genes tending to have longer mRNAs rather than shorter, and is also at a significant subset of loci containing the Histone H3K36me3. GLYR1 is expressed at high levels in most tissue types, including stem cells, and has been found to be overexpressed in breast cancer. GLYR1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Aufreinigung
    Affinity Purified
    Immunogen
    This antibody was raised against a peptide within the C-terminal region of human GLYR1.
    Isotyp
    IgG
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  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified IgG in 70 mM Tris, 105 mM NaCl, 0.07 mM EDTA, 31 mM glycine, 30 % glycerol, and 0.035 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))
    Andere Bezeichnung
    GLYR1 (GLYR1 Produkte)
    Synonyme
    N-PAC antikoerper, BM045 antikoerper, HIBDL antikoerper, NP60 antikoerper, 2810419J22Rik antikoerper, 3930401K13Rik antikoerper, AW545332 antikoerper, Npac antikoerper, 3930401k13rik antikoerper, N-pac antikoerper, RGD1309459 antikoerper, glyoxylate reductase 1 homolog antikoerper, glyoxylate reductase 1 homolog (Arabidopsis) antikoerper, GLYR1 antikoerper, Glyr1 antikoerper
    Molekulargewicht
    65 kDa
    NCBI Accession
    NP_115958
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