PGC1 alpha + beta (AA 601-700) Antikörper (Alexa Fluor 680)

Produktnummer ABIN6944538

Produktdetails

Target: PGC1 alpha + beta

Bindungsspezifität: AA 601-700

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Alexa Fluor 680

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Spezifität: 76 % homology with PGC1 beta

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PPARGC1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: PGC1 alpha + beta

Andere Bezeichnung: PGC1 alpha , beta

Synonyme: LEM6 antikoerper, PGC-1(alpha) antikoerper, PGC-1v antikoerper, PGC1 antikoerper, PGC1A antikoerper, PPARGC1 antikoerper, A830037N07Rik antikoerper, ENSMUSG00000079510 antikoerper, Gm11133 antikoerper, PGC-1 antikoerper, Pgc-1alpha antikoerper, Pgc1 antikoerper, Pgco1 antikoerper, Ppargc1 antikoerper, PPARG coactivator 1 alpha antikoerper, peroxisome proliferative activated receptor, gamma, coactivator 1 alpha antikoerper, PPARGC1A antikoerper, Ppargc1a antikoerper

Hintergrund:

Synonyms: LEM6, PGC-1 Alpha, PGC1 Alpha, Ligand effect modulator 6, Peroxisome prolerative activated receptor, gamma, coactivator 1 alpha, Peroxisome prolerative activated receptor, gamma, coactivator 1 , Peroxisome prolerator activated receptor gamma coactivator 1 alpha, PGC 1 alpha, PGC 1 alpha, PGC 1v, PGC1, PGC1alpha, PGC1A, PGC1v, PPAR gamma coactivator 1 alpha 3 ligand effect modulator 6, PPAR gamma coactivator 1 alpha, PPAR gamma coactivator 1, PPAR gamma coactivator variant form, PPARGC 1 alpha, PPARGC1A.

Background: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene.

Gen-ID: 10891

UniProt: Q9UBK2