PLIN1 Antikörper

Produktnummer ABIN6944484

Produktdetails anti-PLIN1 Antikörper

Target: PLIN1 (Perilipin 1 (PLIN1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PLIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: Full length protein

Klon: 6C2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PLIN1

Target: PLIN1 (Perilipin 1 (PLIN1))

Andere Bezeichnung: Perilipin A (PLIN1 Produkte)

Synonyme: FPLD4 antikoerper, PERI antikoerper, PLIN antikoerper, PERIA antikoerper, Plin antikoerper, 6030432J05Rik antikoerper, Peri antikoerper, peri antikoerper, plin antikoerper, perilipin antikoerper, LOC692833 antikoerper, perilipin 1 antikoerper, perilipin antikoerper, perilipin 1 L homeolog antikoerper, PLIN1 antikoerper, Plin1 antikoerper, plin1 antikoerper, LOC692833 antikoerper, plin1.L antikoerper

Hintergrund:

Synonyms: Perilipin-1, Lipid droplet-associated protein, PLIN1

Background: Perilipins, members of the PAT protein family (named after lipid droplet proteins Perilipin, Adipophilin, and TIP47) are found exclusively at the surface of lipid droplets in adipocytes and steroidogenic cells. They have been suggested to function as regulators of lipolysis and triacylglycerol storage within adipose tissue. Four distinct isoforms ranging from perilipin A (57 kDa) to perilipin D (26 kDa) have been identified and they share an identical amino terminal sequences, and contain 26 consensus protein kinase A (PKA) phosphorylation sites. Perilipin C and D have been detected only in steroidogenic cells. Perilipin A is the most abundant form on the lipid droplets of adipocytes. The phosphorylation of perilipin by PKA, which is accompanied by the phosphorylation and translocation of hormone-sensitive lipase from the cytosol to the lipid droplets, promotes lipolysis. There is evidence for the presence of perilipin A in atheroma plaques suggesting that the protein may be involved in the development of therosclerosis by controlling as in adipocytes the hydrolysis of stored lipids.

Gen-ID: 5346

UniProt: O60240

Pathways: Lipid Metabolism