PDIA6 Antikörper

Produktnummer ABIN6944473

Produktdetails anti-PDIA6 Antikörper

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PDIA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Human PDIA6 between 300 to 500 amino acids

Klon: 4C3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PDIA6

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Andere Bezeichnung: PDIA6 (PDIA6 Produkte)

Synonyme: 1700015E05Rik antikoerper, AL023058 antikoerper, C77895 antikoerper, CaBP5 antikoerper, P5 antikoerper, Txndc7 antikoerper, ERP5 antikoerper, TXNDC7 antikoerper, CaBP1 antikoerper, pdi-p5 antikoerper, erp5 antikoerper, pdia6 antikoerper, pdip5 antikoerper, txndc7 antikoerper, protein disulfide isomerase family A member 6 antikoerper, protein disulfide isomerase associated 6 antikoerper, protein disulfide isomerase family A, member 6 antikoerper, protein disulfide isomerase family A member 6 L homeolog antikoerper, PDIA6 antikoerper, Pdia6 antikoerper, pdia6.L antikoerper

Hintergrund:

Synonyms: Protein disulfide-isomerase A6, Endoplasmic reticulum protein 5, Protein disulfide isomerase P5, Thioredoxin domain-containing protein 7, ER protein 5, ERp5, PDIA6

Background: May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936).

Gen-ID: 10130

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis