OGG1 Antikörper

Produktnummer ABIN6944353

Produktdetails anti-OGG1 Antikörper

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser OGG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: N terminal human OGG1

Klon: 9F3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store for 1 year at -20°C from date of shipment.

Haltbarkeit: 12 months

Details zu OGG1

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Andere Bezeichnung: OGG1 (OGG1 Produkte)

Synonyme: OGG1 antikoerper, zgc:158858 antikoerper, 8-oxoguanine-DNA glycosylase 1 antikoerper, ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1 antikoerper, ATOGG1 antikoerper, F8K7.14 antikoerper, F8K7_14 antikoerper, 19.m02329 antikoerper, DDBDRAFT_0184479 antikoerper, DDBDRAFT_0233024 antikoerper, DDB_0184479 antikoerper, DDB_0233024 antikoerper, ogg1 antikoerper, Tb04.1H19.930 antikoerper, HMMH antikoerper, HOGG1 antikoerper, MUTM antikoerper, OGH1 antikoerper, Mmh antikoerper, 8-oxoguanine DNA glycosylase antikoerper, 8-oxoguanine DNA glycosylase L homeolog antikoerper, 8-oxoguanine-DNA glycosylase 1 antikoerper, 8-OXOGUANINE DNA GLYCOSYLASE antikoerper, putative 8-oxoguanine DNA glycosylase antikoerper, 8-oxoguanine DNA-glycosylase antikoerper, N-glycosylase/DNA lyase OGG1 antikoerper, 8-oxoguanine DNA-glycosylase 1 antikoerper, OGG1 antikoerper, ogg1.L antikoerper, ogg1 antikoerper, ECU08_0770 antikoerper, CA_C2707 antikoerper, BBOV_I004290 antikoerper, Smp_074010.1 antikoerper, LOC9329243 antikoerper, Tb927.4.2480 antikoerper, Ogg1 antikoerper

Hintergrund:

Synonyms: N-glycosylase/DNA lyase, 8-oxoguanine DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase, AP lyase, OGG1, MMH, MUTM, OGH1

Background: DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.

Gen-ID: 4968

UniProt: O15527

Pathways: DNA Reparatur