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CD5 Antikörper (AA 269-366)

CD5 Reaktivität: Human FACS, IHC, IF, StM Wirt: Maus Monoclonal CD5-2418 unconjugated
Produktnummer ABIN6941057
  • Target Alle CD5 Antikörper anzeigen
    CD5
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 269-366
    Reaktivität
    • 228
    • 96
    • 58
    • 27
    • 22
    • 16
    • 15
    • 15
    • 13
    • 12
    • 11
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 173
    • 81
    • 62
    • 1
    Maus
    Klonalität
    • 245
    • 70
    Monoklonal
    Konjugat
    • 113
    • 39
    • 33
    • 29
    • 14
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD5 Antikörper ist unkonjugiert
    Applikation
    • 243
    • 109
    • 68
    • 67
    • 67
    • 54
    • 31
    • 31
    • 22
    • 18
    • 13
    • 13
    • 12
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    Spezifität
    Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)
    Klon
    CD5-2418
    Isotyp
    IgG2c kappa
    Top Product
    Discover our top product CD5 Primärantikörper
  • Applikationshinweise

    Positive Control: 293T, Ramos or MOLT-4 cells. Tonsil or Lymph Node.

    Known Application: Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mg), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    CD5
    Andere Bezeichnung
    CD5 (CD5 Produkte)
    Synonyme
    CD5 antikoerper, Ly-1 antikoerper, Ly-12 antikoerper, Ly-A antikoerper, Lyt-1 antikoerper, LEU1 antikoerper, T1 antikoerper, CD5 molecule antikoerper, CD5 antigen antikoerper, CD5 molecule like antikoerper, Cd5 molecule antikoerper, CD5 antikoerper, Cd5 antikoerper, CD5L antikoerper
    Molekulargewicht
    67kDa
    Gen-ID
    921
    UniProt
    P06127
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