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p63 Antikörper

TP63 Reaktivität: Human IHC, StM Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6940970
  • Target Alle p63 (TP63) Antikörper anzeigen
    p63 (TP63) (Tumor Protein P63 (TP63))
    Reaktivität
    • 70
    • 24
    • 22
    • 4
    • 2
    • 2
    Human
    Wirt
    • 54
    • 20
    • 1
    Kaninchen
    Klonalität
    • 44
    • 31
    Polyklonal
    Konjugat
    • 60
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser p63 Antikörper ist unkonjugiert
    Applikation
    • 46
    • 30
    • 21
    • 16
    • 12
    • 12
    • 12
    • 10
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Immunogen
    Recombinant human p63 protein fragment
    Isotyp
    IgG
    Top Product
    Discover our top product TP63 Primärantikörper
  • Applikationshinweise

    Positive Control: HEK293 cells. Prostate Carcinoma or Lung or bladder squamous cell carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    p63 (TP63) (Tumor Protein P63 (TP63))
    Andere Bezeichnung
    TP63 (TP63 Produkte)
    Synonyme
    AIS antikoerper, B(p51A) antikoerper, B(p51B) antikoerper, EEC3 antikoerper, KET antikoerper, LMS antikoerper, NBP antikoerper, OFC8 antikoerper, RHS antikoerper, SHFM4 antikoerper, TP53CP antikoerper, TP53L antikoerper, TP73L antikoerper, p40 antikoerper, p51 antikoerper, p53CP antikoerper, p63 antikoerper, p73H antikoerper, p73L antikoerper, TP63 antikoerper, tp63 antikoerper, DNp63 antikoerper, id:ibd3516 antikoerper, tp73l antikoerper, wu:fc89f04 antikoerper, wu:fk85h07 antikoerper, wu:fk88b02 antikoerper, Ket antikoerper, P73l antikoerper, Tp73l antikoerper, Trp63 antikoerper, TRP63 antikoerper, AI462811 antikoerper, P51/P63 antikoerper, P63 antikoerper, Tp63 antikoerper, Trp53rp1 antikoerper, Xp63 antikoerper, ket antikoerper, np63 antikoerper, tp73l-A antikoerper, trp63 antikoerper, tumor protein p63 antikoerper, transformation related protein 63 antikoerper, tumor protein p63 L homeolog antikoerper, TP63 antikoerper, tp63 antikoerper, Tp63 antikoerper, Trp63 antikoerper, tp63.L antikoerper
    Hintergrund
    P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
    Molekulargewicht
    63kDa
    Gen-ID
    8626
    UniProt
    Q9H3D4
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