SOX9 Antikörper (AA 393-508)

Produktnummer ABIN6940620

Produktdetails anti-SOX9 Antikörper

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Bindungsspezifität: AA 393-508

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOX9 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human SOX9 protein fragment (around aa 393-508) (exact sequence is proprietary)

Klon: SOX9-2398

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: HepG2 cells. Pancreas.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu SOX9

Target: SOX9 (SRY (Sex Determining Region Y)-Box 9 (SOX9))

Andere Bezeichnung: SOX9 (SOX9 Produkte)

Synonyme: CMD1 antikoerper, CMPD1 antikoerper, SRA1 antikoerper, LOC100227849 antikoerper, 2010306G03Rik antikoerper, AV220920 antikoerper, mKIAA4243 antikoerper, SOX-9 antikoerper, cmd1 antikoerper, cmpd1 antikoerper, sox-9 antikoerper, sox9 antikoerper, sox9-a antikoerper, sox9-b antikoerper, sox9b antikoerper, sra1 antikoerper, SRY-box 9 antikoerper, transcription factor SOX-9 antikoerper, SRY (sex determining region Y)-box 9 antikoerper, SRY box 9 antikoerper, SRY-box 9 L homeolog antikoerper, SOX9 antikoerper, LOC100227849 antikoerper, Sox9 antikoerper, sox9.L antikoerper

Hintergrund: Sox genes comprise a family of genes that are related to the mammalian sex-determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. SOX9 plays an important role in the normal skeletal development. It may regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.

Molekulargewicht: 65kDa

Gen-ID: 6662

UniProt: P48436

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development