Rekombinanter MUC2 Antikörper

Produktnummer ABIN6940119

Produktdetails anti-MUC2 Antikörper

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM), Immunostaining (ISt)

Spezifität: Recognizes a single glycoprotein of 520 kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65 % of colonic carcinomas and about 40 % of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.

Aufreinigung: Purified by Protein A/G

Immunogen: A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH.

Klon: RMLP-842

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: LS174T cells. Human small intestine (IHC).

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu MUC2

Target: MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))

Andere Bezeichnung: MUC2 (MUC2 Produkte)

Synonyme: 2010015E03Rik antikoerper, MCM antikoerper, wnn antikoerper, MLP antikoerper, MUC-2 antikoerper, SMUC antikoerper, HH-Muc antikoerper, mucin 2 antikoerper, mucin 2, oligomeric mucus/gel-forming antikoerper, mucin-2 antikoerper, Muc2 antikoerper, MUC2 antikoerper, LOC100724045 antikoerper

Molekulargewicht: 520kDa

Gen-ID: 4583

UniProt: Q02817