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MUC1 Antikörper

MUC1 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal MUC1-520 unconjugated
Produktnummer ABIN6940099
  • Target Alle MUC1 Antikörper anzeigen
    MUC1 (Mucin 1 (MUC1))
    Reaktivität
    • 274
    • 58
    • 30
    • 12
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 197
    • 90
    • 2
    • 1
    Maus
    Klonalität
    • 175
    • 110
    • 5
    Monoklonal
    Konjugat
    • 146
    • 26
    • 16
    • 12
    • 11
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser MUC1 Antikörper ist unkonjugiert
    Applikation
    • 142
    • 137
    • 101
    • 86
    • 75
    • 48
    • 26
    • 25
    • 24
    • 20
    • 19
    • 14
    • 13
    • 13
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    In Western blotting, it recognizes proteins in MW range of 265-400 kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Human milk-fat globule membranes (HMFGM)
    Klon
    MUC1-520
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product MUC1 Primärantikörper
  • Applikationshinweise

    Positive Control: MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    MUC1 (Mucin 1 (MUC1))
    Andere Bezeichnung
    MUC1 (MUC1 Produkte)
    Synonyme
    CA 15-3 antikoerper, CD227 antikoerper, EMA antikoerper, H23AG antikoerper, KL-6 antikoerper, MAM6 antikoerper, MCKD1 antikoerper, MUC-1 antikoerper, MUC-1/SEC antikoerper, MUC-1/X antikoerper, MUC1/ZD antikoerper, PEM antikoerper, PEMT antikoerper, PUM antikoerper, Muc-1 antikoerper, mucin 1, cell surface associated antikoerper, mucin 1, transmembrane antikoerper, MUC1 antikoerper, Muc1 antikoerper
    Molekulargewicht
    265-400kDa
    Gen-ID
    4582
    UniProt
    P15941
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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