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PLAP Antikörper

ALPP Reaktivität: Human IHC, ISt Wirt: Maus Monoclonal ALP-870 unconjugated
Produktnummer ABIN6939451
  • Target Alle PLAP (ALPP) Antikörper anzeigen
    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
    Reaktivität
    • 128
    • 22
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 75
    • 53
    • 2
    Maus
    Klonalität
    • 68
    • 61
    Monoklonal
    Konjugat
    • 70
    • 11
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PLAP Antikörper ist unkonjugiert
    Applikation
    • 94
    • 53
    • 53
    • 36
    • 23
    • 19
    • 14
    • 13
    • 12
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunostaining (ISt)
    Spezifität
    Reacts with a 70 kDa membrane-bound isozyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. It is highly specific for PLAP and shows no cross-reaction with other isozymes of alkaline phosphatase. Anti-PLAP reacts with germ cell tumors and can discriminate between these and other neoplasms. Somatic neoplasms e.g. breast, gastrointestinal, prostatic, and urinary cancers may also immunoreact with antibodies to PLAP. Anti-PLAP positivity in conjunction with anti-keratin negativity favors seminoma over carcinoma. Germ cell tumors are usually anti-keratin positive, but they regularly fail to stain with anti-EMA, whereas most carcinomas stain with anti-EMA. Anti-PLAP has been useful in the diagnosis of gestational trophoblastic disease.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human ALPP protein
    Klon
    ALP-870
    Isotyp
    IgG
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  • Applikationshinweise

    Positive Control: HepG2 cells. Placenta or seminoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(No special pretreatment is required for the immunohistochemical staining of formalin-fixed tissues.)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
    Andere Bezeichnung
    ALPP (ALPP Produkte)
    Synonyme
    ECK0378 antikoerper, JW0374 antikoerper, psiA antikoerper, ALP antikoerper, PALP antikoerper, PLAP antikoerper, PLAP-1 antikoerper, ILC antikoerper, CTACK antikoerper, ESkine antikoerper, Akp2 antikoerper, alp antikoerper, zgc:56672 antikoerper, DDBDRAFT_0205491 antikoerper, DDBDRAFT_0231570 antikoerper, DDB_0205491 antikoerper, DDB_0231570 antikoerper, ALPI antikoerper, Actn2lp antikoerper, Alp antikoerper, bacterial alkaline phosphatase antikoerper, alkaline phosphatase, placental antikoerper, alkaline phosphatase, placental type antikoerper, C-C motif chemokine ligand 27 antikoerper, alkaline phosphatase, liver/bone/kidney antikoerper, alkaline phosphatase antikoerper, alkaline phosphatase, intestinal antikoerper, PDZ and LIM domain 3 antikoerper, phoA antikoerper, ALPP antikoerper, LOC100436725 antikoerper, CCL27 antikoerper, alpl antikoerper, alp antikoerper, ALPI antikoerper, Pdlim3 antikoerper, Alpp antikoerper
    Molekulargewicht
    70kDa
    Gen-ID
    250
    UniProt
    P05187
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