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CNTF Receptor alpha Antikörper (AA 151-160)

CNTFR Reaktivität: Human WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN687637
  • Target Alle CNTF Receptor alpha (CNTFR) Antikörper anzeigen
    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
    Bindungsspezifität
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-160
    Reaktivität
    • 34
    • 29
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 2
    • 1
    Kaninchen
    Klonalität
    • 44
    • 1
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CNTF Receptor alpha Antikörper ist unkonjugiert
    Applikation
    • 28
    • 13
    • 13
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CNTFR Alpha
    Isotyp
    IgG
    Top Product
    Discover our top product CNTFR Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Schwieger, Warnecke, Lenarz, Esser, Scheper: "Neuronal Survival, Morphology and Outgrowth of Spiral Ganglion Neurons Using a Defined Growth Factor Combination." in: PLoS ONE, Vol. 10, Issue 8, pp. e0133680, (2015) (PubMed).

  • Target
    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))
    Andere Bezeichnung
    CNTF Receptor alpha (CNTFR Produkte)
    Synonyme
    CNTFR-alpha antikoerper, CNTFRALPHA antikoerper, Cntfralpha antikoerper, cb549 antikoerper, fj33e02 antikoerper, sb:cb549 antikoerper, wu:fj33e02 antikoerper, si:bz76a6.1 antikoerper, si:dz248f2.1 antikoerper, si:rp71-76a6.1 antikoerper, ciliary neurotrophic factor receptor antikoerper, ciliary neurotrophic factor receptor L homeolog antikoerper, CNTFR antikoerper, cntfr.L antikoerper, Cntfr antikoerper, cntfr antikoerper
    Hintergrund

    Synonyms: Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alpha, CNTFR

    Background: CNTF Receptor alpha is a receptor belonging to the cytokine superfamily of receptors. Along with LIFR and gp130, CNTF Receptor alpha forms the heterotrimeric CNTF receptor complex. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. During signal transduction, CNTF first binds to CNTF Recepror alpha, and this permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified.

    Gen-ID
    1271
    UniProt
    P26992
    Pathways
    JAK-STAT Signalweg, Feeding Behaviour
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