SUMO1 Antikörper (AA 21-101)
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- Target Alle SUMO1 Antikörper anzeigen
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
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Bindungsspezifität
- AA 21-101
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Reaktivität
- Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SUMO1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- There is a chance that this antibody will cross-react with SUMO13
- Kreuzreaktivität
- Maus, Ratte
- Homologie
- Human,Cow,Pig,Horse,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SUMO 1
- Isotyp
- IgG
- Top Product
- Discover our top product SUMO1 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- SUMO1 (Small Ubiquitin Related Modifier Protein 1 (SUMO1))
- Andere Bezeichnung
- SUMO 1 (SUMO1 Produkte)
- Synonyme
- DAP1 antikoerper, GMP1 antikoerper, OFC10 antikoerper, PIC1 antikoerper, SENP2 antikoerper, SMT3 antikoerper, SMT3C antikoerper, SMT3H3 antikoerper, UBL1 antikoerper, hm:zeh0670 antikoerper, wu:fb74c02 antikoerper, wu:fd12c02 antikoerper, zgc:65934 antikoerper, zgc:85634 antikoerper, SUMO1 antikoerper, dap1 antikoerper, gmp1 antikoerper, ofc10 antikoerper, pic1 antikoerper, senp2 antikoerper, smt3 antikoerper, smt3c antikoerper, sumo-1 antikoerper, sumo1 antikoerper, ubl1 antikoerper, xsumo-1 antikoerper, xsumo1 antikoerper, ARABIDOPSIS THALIANA SMALL UBIQUITIN-LIKE MODIFIER 1 antikoerper, ATSUMO1 antikoerper, F10M23.180 antikoerper, F10M23_180 antikoerper, SMALL UBIQUITIN-LIKE MODIFIER 1 antikoerper, SUM1 antikoerper, SUMO 1 antikoerper, small ubiquitin-like modifier 1 antikoerper, pigSUMO1 antikoerper, SENTRIN antikoerper, SMTP3 antikoerper, SUMO-1 antikoerper, Smt3C antikoerper, Ubl1 antikoerper, small ubiquitin-like modifier 1 antikoerper, small ubiquitin-like modifier 1 S homeolog antikoerper, small ubiquitin-related protein 1 antikoerper, SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) antikoerper, SMT3 suppressor of mif two 3 homolog 1 (yeast) antikoerper, small ubiquitin-like modifier 1 L homeolog antikoerper, Sumo1 antikoerper, SUMO1 antikoerper, sumo1 antikoerper, sumo1.S antikoerper, sumo-1 antikoerper, sumo1.L antikoerper
- Hintergrund
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Synonyms: Small ubiquitin-related modifier 1, SUMO-1, GAP-modifying protein 1, GMP1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Smt3C, Ubiquitin-like protein UBL1, SUMO1, SMT3C, SMT3H3, UBL1, OK/SW-cl.43
Background: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. May also regulate a network of genes involved in palate development.
- Gen-ID
- 7341
- UniProt
- P63165
- Pathways
- M Phase, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, Ubiquitin Proteasome Pathway
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