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Bcl-2 Antikörper (pSer70)

BCL2 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN683428
  • Target Alle Bcl-2 (BCL2) Antikörper anzeigen
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Bindungsspezifität
    • 54
    • 36
    • 23
    • 22
    • 21
    • 18
    • 17
    • 16
    • 16
    • 16
    • 15
    • 14
    • 13
    • 10
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer70
    Reaktivität
    • 453
    • 189
    • 186
    • 38
    • 34
    • 22
    • 22
    • 19
    • 17
    • 16
    • 12
    • 5
    • 5
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 357
    • 124
    • 6
    • 2
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 353
    • 138
    Polyklonal
    Konjugat
    • 217
    • 35
    • 34
    • 25
    • 25
    • 15
    • 14
    • 13
    • 11
    • 11
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Bcl-2 Antikörper ist unkonjugiert
    Applikation
    • 395
    • 200
    • 167
    • 123
    • 106
    • 103
    • 91
    • 75
    • 63
    • 33
    • 28
    • 25
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus, Ratte
    Homologie
    Dog,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70
    Isotyp
    IgG
    Top Product
    Discover our top product BCL2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Yan, Yuan, Gao, Huang, Ma, Gao, Zhang, Guo, Chen: "Overexpression of Human E46K Mutant ?-Synuclein Impairs Macroautophagy via Inactivation of JNK1-Bcl-2 Pathway." in: Molecular neurobiology, Vol. 50, Issue 2, pp. 685-701, (2014) (PubMed).

  • Target
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    Andere Bezeichnung
    Bcl-2 (BCL2 Produkte)
    Synonyme
    Bcl-2 antikoerper, PPP1R50 antikoerper, bcl-2 antikoerper, AW986256 antikoerper, C430015F12Rik antikoerper, D630044D05Rik antikoerper, D830018M01Rik antikoerper, BCL-2 antikoerper, Bcl2 antikoerper, BCL2, apoptosis regulator antikoerper, B cell leukemia/lymphoma 2 antikoerper, B-cell CLL/lymphoma 2a antikoerper, B-cell CLL/lymphoma 2 protein antikoerper, BCL2 antikoerper, Bcl2 antikoerper, bcl2a antikoerper, BCL-2 antikoerper
    Hintergrund

    Synonyms: Bcl-2, Apoptosis regulator Bcl-2, Bcl2

    Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).

    Gen-ID
    24224
    UniProt
    P49950
    Pathways
    MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagie, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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