Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

GAPDH Antikörper (AA 1-335)

GAPDH Reaktivität: Human, Maus, Ratte, Kaninchen, Schwein, Huhn, Rind (Kuh), Diverse Spezies WB, IHC (p), FACS, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN678458
  • Target Alle GAPDH Antikörper anzeigen
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    Bindungsspezifität
    • 37
    • 20
    • 13
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-335
    Reaktivität
    • 222
    • 141
    • 134
    • 74
    • 64
    • 54
    • 35
    • 28
    • 23
    • 21
    • 20
    • 19
    • 18
    • 15
    • 12
    • 12
    • 11
    • 10
    • 9
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Schwein, Huhn, Rind (Kuh), Diverse Spezies
    Wirt
    • 169
    • 97
    • 17
    • 10
    • 4
    Kaninchen
    Klonalität
    • 190
    • 105
    Polyklonal
    Konjugat
    • 156
    • 36
    • 23
    • 17
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GAPDH Antikörper ist unkonjugiert
    Applikation
    • 243
    • 98
    • 84
    • 70
    • 45
    • 41
    • 40
    • 35
    • 15
    • 15
    • 15
    • 14
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Huhn, Rind (Kuh), Human, Maus, Schwein, Kaninchen, Ratte, Diverse Spezies
    Aufreinigung
    Purified by Protein A.
    Immunogen
    GAPDH protein of rabbit
    Isotyp
    IgG
    Top Product
    Discover our top product GAPDH Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Zhang, Wang, Xie, Chen, Sinkemani, Yu, Wang, Mao, Wu: "Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence." in: Oncotarget, Vol. 9, Issue 2, pp. 2175-2192, (2018) (PubMed).

    Sun, Zhang, Tang, Yang, Chu, Zhao: "SL2B aptamer and folic acid dual-targeting DNA nanostructures for synergic biological effect with chemotherapy to combat colorectal cancer." in: International journal of nanomedicine, Vol. 12, pp. 2657-2672, (2017) (PubMed).

    Tan, Shi, Ba, Lin, Tang, Zeng, Zhang: "miR-409-3p sensitizes colon cancer cells to oxaliplatin by inhibiting Beclin-1-mediated autophagy." in: International journal of molecular medicine, Vol. 37, Issue 4, pp. 1030-8, (2016) (PubMed).

    Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: "Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats." in: Molecular medicine reports, Vol. 13, Issue 6, pp. 4627-35, (2016) (PubMed).

    Wang, Jia, Chen, Wang, Li: "Osthole shows the potential to overcome P-glycoprotein‑mediated multidrug resistance in human myelogenous leukemia K562/ADM cells by inhibiting the PI3K/Akt signaling pathway." in: Oncology reports, Vol. 35, Issue 6, pp. 3659-68, (2016) (PubMed).

    Xiong, Luo, He, Xi, Lu, Li, Liu, Guo: "Up-regulation of miR-138 inhibits hypoxia-induced cardiomyocyte apoptosis via down-regulating lipocalin-2 expression." in: Experimental biology and medicine (Maywood, N.J.), Vol. 241, Issue 1, pp. 25-30, (2016) (PubMed).

    Yang, Yao, Qian, Wei, Wu, Wang: "Rab5-mediated VE-cadherin internalization regulates the barrier function of the lung microvascular endothelium." in: Cellular and molecular life sciences : CMLS, Vol. 72, Issue 24, pp. 4849-66, (2016) (PubMed).

    Hou, Liu, Chai, Yu, Duan, Hu, Yin, Wang, Zhuang, Fan, Chu, Ma: "Lipopolysaccharide pretreatment inhibits LPS-induced human umbilical cord mesenchymal stem cell apoptosis via upregulating the expression of cellular FLICE-inhibitory protein." in: Molecular medicine reports, Vol. 12, Issue 2, pp. 2521-8, (2015) (PubMed).

    Zhang, Shi, Lin, Ba, Cui: "MicroRNA-216a enhances the radiosensitivity of pancreatic cancer cells by inhibiting beclin-1-mediated autophagy." in: Oncology reports, Vol. 34, Issue 3, pp. 1557-64, (2015) (PubMed).

    Shao, Qian, Wang, Yan, Hu, Wang, Wang: "Construction of the plasmid coding for the expression of the EGFP-M-IL-2((88)Arg, (125)Ala) fusion protein and the anti-tumor effects exerted by the fusion protein in HeLa-60 cells." in: Oncology letters, Vol. 9, Issue 6, pp. 2729-2735, (2015) (PubMed).

    Zhang, Feng, Tao, DE, Chang, Hu: "Increased stathmin expression strengthens fear conditioning in epileptic rats." in: Biomedical reports, Vol. 3, Issue 1, pp. 28-32, (2015) (PubMed).

    Song, Xiao, Fu, Huang, Wang, Zhang, Yang: "Increased expression of the pluripotency markers sex-determining region Y-box 2 and Nanog homeobox in ovarian endometriosis." in: Reproductive biology and endocrinology : RB&E, Vol. 12, pp. 42, (2014) (PubMed).

    Yan, Yang, Li, Duan, Wu, Qian, Li, Wang: "Regulator of calcineurin 1-1L protects cardiomyocytes against hypoxia-induced apoptosis via mitophagy." in: Journal of cardiovascular pharmacology, Vol. 64, Issue 4, pp. 310-7, (2014) (PubMed).

    Steenblock, Heckel, Czupalla, Espírito Santo, Niehage, Sztacho, Hoflack: "The Cdc42 guanine nucleotide exchange factor FGD6 coordinates cell polarity and endosomal membrane recycling in osteoclasts." in: The Journal of biological chemistry, Vol. 289, Issue 26, pp. 18347-59, (2014) (PubMed).

    Li, McFadden, Morgan, Cui, Hu, Wan, Zeng: "All-trans retinoic acid regulates the expression of the extracellular matrix protein fibulin-1 in the guinea pig sclera and human scleral fibroblasts." in: Molecular vision, Vol. 16, pp. 689-97, (2010) (PubMed).

  • Target
    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))
    Andere Bezeichnung
    Gapdh (GAPDH Produkte)
    Synonyme
    G3PD antikoerper, GAPD antikoerper, Gapd antikoerper, BEST:GH12586 antikoerper, CG12055 antikoerper, Dmel\\CG12055 antikoerper, GA3PDH antikoerper, GADPH antikoerper, GAP antikoerper, GAPDH antikoerper, GAPDH I antikoerper, GAPDH-1 antikoerper, GAPDH1 antikoerper, GAPDHI antikoerper, Gapdh antikoerper, Gapdh-1 antikoerper, Gapdh43E antikoerper, gadph antikoerper, gapdh antikoerper, gapdh-1 antikoerper, gh12586 antikoerper, cb609 antikoerper, gapd antikoerper, mg:bb02e05 antikoerper, wu:fb33a10 antikoerper, wu:ft80f05 antikoerper, KNC-NDS6 antikoerper, g3pd antikoerper, G3PDH antikoerper, glyceraldehyde-3-phosphate dehydrogenase antikoerper, Glyceraldehyde 3 phosphate dehydrogenase 1 antikoerper, glyceraldehyde-3-phosphate dehydrogenase S homeolog antikoerper, glyceraldehyde-3-phosphate dehydrogenase, type I antikoerper, olfactory receptor 8K3 antikoerper, GAPDH antikoerper, Gapdh antikoerper, Gapdh1 antikoerper, gapdh antikoerper, gapdh.S antikoerper, gapDH antikoerper, LOC100404960 antikoerper, LOC614985 antikoerper
    Hintergrund

    Synonyms: G3PD, GAPD, HEL-S-162eP, Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Peptidyl-cysteine S-nitrosylase GAPDH, CDABP47, OK/SW-cl.12

    Background: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.

    Gen-ID
    2597
    UniProt
    P04406
Sie sind hier:
Kundenservice