IGF2BP3 Antikörper (AA 101-230)

Produktnummer ABIN674814

Produktdetails anti-IGF2BP3 Antikörper

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Bindungsspezifität: AA 101-230

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGF2BP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Insulin-like growth factor 2 mRNA-binding protein 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu IGF2BP3

Target: IGF2BP3 (Insulin-Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3))

Andere Bezeichnung: IGF2BP3 (IGF2BP3 Produkte)

Synonyme: CT98 antikoerper, IMP-3 antikoerper, IMP3 antikoerper, KOC1 antikoerper, VICKZ3 antikoerper, Ab2-255 antikoerper, RGD1306512 antikoerper, imp3 antikoerper, koc1 antikoerper, vera antikoerper, imp-3 antikoerper, vg1rbp antikoerper, vickz3 antikoerper, 2610101N11Rik antikoerper, AA522010 antikoerper, AL022933 antikoerper, AU045931 antikoerper, Koc13 antikoerper, Neilsen antikoerper, mimp3 antikoerper, dvr1rbp antikoerper, wu:fb79c12 antikoerper, wu:fe06h09 antikoerper, zVg1RBP antikoerper, B3 antikoerper, IGF2 mRNA-binding protein 3-B antikoerper, IMP antikoerper, IMP-3-B antikoerper, Vg1 RBP-B antikoerper, Vg1-RBP antikoerper, igf2bp3 antikoerper, igf2bp3-a antikoerper, igf2bp3-b antikoerper, IGF2 mRNA-binding protein 3-A antikoerper, IMP-3-A antikoerper, Vg1 RBP-A antikoerper, vera-A antikoerper, insulin like growth factor 2 mRNA binding protein 3 antikoerper, insulin-like growth factor 2 mRNA binding protein 3 antikoerper, insulin like growth factor 2 mRNA binding protein 3 S homeolog antikoerper, insulin like growth factor 2 mRNA binding protein 3 L homeolog antikoerper, IGF2BP3 antikoerper, Igf2bp3 antikoerper, igf2bp3 antikoerper, igf2bp3.S antikoerper, igf2bp3.L antikoerper

Hintergrund:

Synonyms: KOC, CT98, IMP3, KOC1, IMP-3, VICKZ3, Insulin-like growth factor 2 mRNA-binding protein 3, IGF2 mRNA-binding protein 3, IGF-II mRNA-binding protein 3, KH domain-containing protein overexpressed in cancer, hKOC, VICKZ family member 3, IGF2BP3

Background: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.

Gen-ID: 10643

UniProt: O00425