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HLA-E Antikörper (AA 251-358)

HLA-E Reaktivität: Human WB, FACS, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN674334
  • Target Alle HLA-E Antikörper anzeigen
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Bindungsspezifität
    • 15
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-358
    Reaktivität
    • 70
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 28
    Kaninchen
    Klonalität
    • 45
    • 26
    Polyklonal
    Konjugat
    • 30
    • 6
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HLA-E Antikörper ist unkonjugiert
    Applikation
    • 42
    • 28
    • 19
    • 12
    • 12
    • 11
    • 10
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HLA E
    Isotyp
    IgG
    Top Product
    Discover our top product HLA-E Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Sun, Xu, Huang, Huang, Wen, Zhang, Wang, Song, Zheng, Sun, Wei, Xiao, Sun, Tian: "High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer." in: Oncoimmunology, Vol. 6, Issue 1, pp. e1264562, (2017) (PubMed).

  • Target
    HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
    Andere Bezeichnung
    HLA E (HLA-E Produkte)
    Synonyme
    EA1.2 antikoerper, EA2.1 antikoerper, HLA-6.2 antikoerper, MHC antikoerper, QA1 antikoerper, major histocompatibility complex, class I, E antikoerper, HLA-E antikoerper, PATR-E antikoerper
    Hintergrund

    Synonyms: MHC, QA1, EA1.2, EA2.1, HLA-6.2, HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen E, HLA-E, HLAE

    Background: HLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules.

    Gen-ID
    3133
    UniProt
    P13747
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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