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Macrophage Mannose Receptor 1 Antikörper (FITC)

MRC1 Reaktivität: Maus FACS, ICFC Wirt: Ratte Monoclonal C068C2 FITC
Produktnummer ABIN6727447
  • Target Alle Macrophage Mannose Receptor 1 (MRC1) Antikörper anzeigen
    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
    Reaktivität
    • 72
    • 42
    • 23
    • 16
    • 1
    • 1
    Maus
    Wirt
    • 43
    • 31
    • 16
    Ratte
    Klonalität
    • 45
    • 41
    Monoklonal
    Konjugat
    • 36
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Macrophage Mannose Receptor 1 Antikörper ist konjugiert mit FITC
    Applikation
    • 53
    • 52
    • 23
    • 16
    • 13
    • 11
    • 9
    • 9
    • 6
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
    Klon
    C068C2
    Isotyp
    IgG2a, kappa
    Top Product
    Discover our top product MRC1 Primärantikörper
  • Applikationshinweise
    Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
    Kommentare

    Matching Isotype Control: FITC Rat IgG2a, κ Isotype Control (ABIN7469839)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Proclin300, 1 % BSA
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • Target
    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
    Andere Bezeichnung
    CD206 (MRC1 Produkte)
    Synonyme
    CD206 antikoerper, CLEC13D antikoerper, CLEC13DL antikoerper, MMR antikoerper, MRC1L1 antikoerper, bA541I19.1 antikoerper, AW259686 antikoerper, MR antikoerper, mrc1 antikoerper, MGC86525 antikoerper, MRC1 antikoerper, MRC1L-A antikoerper, mannose receptor C-type 1 antikoerper, mannose receptor, C type 1 antikoerper, mannose receptor C-type 1 L homeolog antikoerper, mediator of replication checkpoint 1 antikoerper, MRC1 antikoerper, Mrc1 antikoerper, mrc1.L antikoerper, mrc1 antikoerper
    Hintergrund
    MMR,MR,MRC1,macrophage mannose receptor,mannose receptor,CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
    Gen-ID
    17533
    UniProt
    Q61830
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