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PD-L1 Antikörper

PD-L1 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 10F-9G2 unconjugated
Produktnummer ABIN6727404
  • Target Alle PD-L1 Antikörper anzeigen
    PD-L1 (CD274 (PD-L1))
    Reaktivität
    • 170
    • 108
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Maus
    Wirt
    • 126
    • 62
    • 17
    • 4
    • 4
    • 1
    Ratte
    Klonalität
    • 108
    • 104
    • 2
    Monoklonal
    Konjugat
    • 98
    • 16
    • 13
    • 11
    • 9
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Dieser PD-L1 Antikörper ist unkonjugiert
    Applikation
    • 139
    • 104
    • 60
    • 40
    • 37
    • 28
    • 17
    • 17
    • 16
    • 15
    • 10
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    Purified
    Klon
    10F-9G2
    Isotyp
    IgG2b, kappa
    Top Product
    Discover our top product PD-L1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    Matching Isotype Control: Purified Rat IgG2b, κ Isotype Control (ABIN7469856)

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS with 0.05 % Proclin300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2~8°C. Do not freeze.
  • Target
    PD-L1 (CD274 (PD-L1))
    Andere Bezeichnung
    CD274/PD-L1 (PD-L1 Produkte)
    Synonyme
    B7-H antikoerper, B7H1 antikoerper, PD-L1 antikoerper, PDCD1L1 antikoerper, PDCD1LG1 antikoerper, PDL1 antikoerper, A530045L16Rik antikoerper, B7h1 antikoerper, Pdcd1l1 antikoerper, Pdcd1lg1 antikoerper, Pdl1 antikoerper, RGD1566211 antikoerper, CD274 molecule antikoerper, CD274 antigen antikoerper, programmed cell death 1 ligand 2 antikoerper, CD274 antikoerper, Cd274 antikoerper, PDCD1LG2 antikoerper
    Hintergrund
    B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin receptor superfamily. It is expressed on T cells, B cells, NK cells, dendritic cells, IFN-γ activated endothelial cells, and monocytes. B7-H1 is one of the ligands of PD-1. The interaction of B7-H1 with PD-1 plays an important role in the inhibition of T cell responses. Other studies have shown that B7-H1 is able to costimulate T cell growth and cytokine production. CD274 is involved in costimulation essential for T cell proliferation and production of IL-10 and IFN-γ, in an IL-2-dependent and a PD-1-independent manner. Its interaction with PD-1 inhibits T cell proliferation and cytokine production.
    Gen-ID
    60533
    UniProt
    Q9EP73
    Pathways
    Cancer Immune Checkpoints
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