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Cyclin D3 Antikörper (AA 121-220)

CCND3 Reaktivität: Human, Kaninchen WB, ELISA, IF (cc), IHC (p), IF (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN671571
  • Target Alle Cyclin D3 (CCND3) Antikörper anzeigen
    Cyclin D3 (CCND3)
    Bindungsspezifität
    • 33
    • 15
    • 11
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220
    Reaktivität
    • 114
    • 50
    • 39
    • 15
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Kaninchen
    Wirt
    • 99
    • 17
    Kaninchen
    Klonalität
    • 90
    • 26
    Polyklonal
    Konjugat
    • 53
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cyclin D3 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 34
    • 33
    • 26
    • 25
    • 19
    • 15
    • 14
    • 9
    • 8
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Kaninchen
    Homologie
    Mouse,Rat,Dog,Cow,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Cyclin D3
    Isotyp
    IgG
    Top Product
    Discover our top product CCND3 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Souza, Silva, Calloway, Kucuk, Rossi, McLemore: "Genistein protects hematopoietic stem cells against G-CSF-induced DNA damage." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 5, pp. 534-44, (2014) (PubMed).

  • Target
    Cyclin D3 (CCND3)
    Andere Bezeichnung
    Cyclin D3 (CCND3 Produkte)
    Synonyme
    zgc:103502 antikoerper, CCND3 antikoerper, 9230106B05Rik antikoerper, AA682053 antikoerper, AL024085 antikoerper, AW146355 antikoerper, C78795 antikoerper, cyclin D3 antikoerper, ccnd3 antikoerper, CCND3 antikoerper, Ccnd3 antikoerper
    Hintergrund

    Synonyms: G1/S-specific cyclin-D3, CCND3

    Background: Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D3/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.

    Gen-ID
    896
    UniProt
    P30281
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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