p38 Antikörper (MAP kinase p38) (AA 160-210)

Details for Product anti-p38 Antibody No. ABIN671241, Anbieter: Anmelden zum Anzeigen
Antigen
  • CSBP
  • CSBP1
  • CSBP2
  • CSPB1
  • EXIP
  • Mxi2
  • PRKM14
  • PRKM15
  • RK
  • SAPK2A
  • p38
  • p38ALPHA
  • CRK1
  • Csbp1
  • Csbp2
  • Exip
  • Hog
  • Prkm14
  • Prkm15
  • Sapk2A
  • p38Hog
  • p38alpha
  • Crk1
  • p38-alpha
  • p38MAPK
  • p38a
  • MAP kinase 14A
  • MAP kinase p38a
  • MAPK 14A
  • MAPK14
  • fk28c03
  • hm:zeh1243
  • wu:fk28c03
  • zp38a
  • P38C-CRK
  • mitogen-activated protein kinase 14
  • mitogen activated protein kinase 14
  • mitogen-activated protein kinase 14a
  • CRK proto-oncogene, adaptor protein
  • MAPK14
  • Mapk14
  • mapk14a
  • CRK
Epitop
AA 160-210
69
62
31
15
14
11
10
7
6
5
5
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
335
272
264
56
41
41
40
38
38
37
37
37
16
15
15
1
1
1
Wirt
Kaninchen
231
106
Klonalität
Polyklonal
Konjugat
Dieser p38 Antikörper ist unkonjugiert
9
9
9
7
7
6
5
5
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
280
207
141
103
69
61
59
27
26
23
18
12
8
6
2
1
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide derived from human P38MAPK
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere p38 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung P38 MAPK (p38 Antibody Abstract)
Hintergrund

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Subcellular location: Cytoplasm, Nucleus

Synonyms: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA, Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, MAPK14

Gen-ID 1432
UniProt Q16539
Pathways MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Hepatitis C, Toll-Like Receptors Cascades, Autophagie, Thromboxane A2 Receptor Signaling
Applikations-hinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-MAP kinase p38 (p38) (AA 160-210) antibody (ABIN671241) Formalin-fixed and paraffin embedded mouse embryo labeled with Rabbit Anti p38MAPK/MA...
Immunohistochemistry (IHC) image for anti-MAP kinase p38 (p38) (AA 160-210) antibody (ABIN671241) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti p38MAPK/MAPK1...
Western Blotting (WB) image for anti-MAP kinase p38 (p38) (AA 160-210) antibody (ABIN671241) Independently Validated Antibody, image provided by Science Exchange, badge number 02...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-MAP kinase p38 (p38) (AA 160-210) antibody (ABIN671241) MCF-7 cells were stained with p38 MAPK Polyclonal Antibody, Unconjugated at 1:500 in ...
Produkt verwendet in: Ning, Wang, Gao, Mu, Wang, Liu, Zhu, Meng: "Chicory inulin ameliorates type 2 diabetes mellitus and suppresses JNK and MAPK pathways in vivo and in vitro." in: Molecular nutrition & food research, 2017 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB), Western Blotting (WB) (Probematerial (Species): Rat (Rattus)).

Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 192-200, 2017 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: lung

Li, Cheng, Nie, Lai, Hu, Luo, Li, Li et al.: "Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt ..." in: Biological trace element research, 2017 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Shi, Zhan, Zhao, Wang, Ma: "Effects of Fluoride on the Expression of p38MAPK Signaling Pathway-Related Genes and Proteins in Spleen Lymphocytes of Mice." in: Biological trace element research, Vol. 173, Issue 2, pp. 333-8, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Zhang, Zang, Dong, Liu, Wang, Yan, Xu, Liu, Pang: "Effect of vasopressin on hippocampal injury in a rodent model of asphyxial cardiopulmonary arrest." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1385-1392, 2016 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: brain

Cai, He, Li, Sun, Lam, Qiao, Qiu: "Regulation of tumorigenesis in oral epithelial cells by defined reprogramming factors Oct4 and Sox2." in: Oncology reports, Vol. 36, Issue 2, pp. 651-8, 2016 (PubMed). Von den Autoren verwendete Methode: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Probematerial (Species): Mouse (Murine)). Weitere Details: Sample: tongue

Cong, Chen: "Neuroprotective Effect of Ginsenoside Rd in Spinal Cord Injury Rats." in: Basic & clinical pharmacology & toxicology, Vol. 119, Issue 2, pp. 193-201, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)).

Yu, Shi, Qi, Zhao, Gao, Li: "Gypenoside Protects Cardiomyocytes against Ischemia-Reperfusion Injury via the Inhibition of Mitogen-Activated Protein Kinase Mediated Nuclear Factor Kappa B Pathway In Vitro and In Vivo." in: Frontiers in pharmacology, Vol. 7, pp. 148, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB), Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: ischemic penumbra

Zhao, Xue, Guo, Sun, Liu, Wang: "Inhibition of endocan attenuates monocrotaline-induced connective tissue disease related pulmonary arterial hypertension." in: International immunopharmacology, Vol. 42, pp. 115-121, 2016 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB), Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: Lung

Zhao, Liu, Liu, Han, Zhao: "Betulin attenuates lung and liver injuries in sepsis." in: International immunopharmacology, Vol. 30, pp. 50-6, 2015 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)). Weitere Details: Sample: Lung

Li, Dong, Song, Xu, Liu, Song: "Nrf2/ARE pathway activation, HO-1 and NQO1 induction by polychlorinated biphenyl quinone is associated with reactive oxygen species and PI3K/AKT signaling." in: Chemico-biological interactions, Vol. 209, pp. 56-67, 2014 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Human).

Wang, Zhu, Man, Guo, Hao: "Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury." in: Neural regeneration research, Vol. 9, Issue 18, pp. 1678-87, 2014 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Rat (Rattus)).

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