COL18A1 Antikörper (AA 1581-1680)

Produktnummer ABIN669951

Produktdetails anti-COL18A1 Antikörper

Target: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Bindungsspezifität: AA 1581-1680

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL18A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COL18A1/Endostatin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-COL18A1 Antikörper (ABIN669951)

Imoto, Kumatani, Okada, Yamawaki: "Endostatin is protective against monocrotaline-induced right heart disease through the inhibition of T-type Ca(2+) channel." in: Pflügers Archiv : European journal of physiology, Vol. 468, Issue 7, pp. 1259-70, (2016) (PubMed).

Hu, Hu, Zhang, Jia, Qian, Yang, Li: "Clinical significance of serum and tumor tissue endostatin evaluation in operable non-small cell lung cancer." in: Biomedical reports, Vol. 2, Issue 6, pp. 898-904, (2014) (PubMed).

Gao, Zhao, Liang, Li, Cao, Liu: "Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients." in: Nephrology (Carlton, Vic.), Vol. 16, Issue 8, pp. 736-42, (2011) (PubMed).

Details zu COL18A1

Target: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Andere Bezeichnung: COL18A1 (COL18A1 Produkte)

Synonyme: KNO antikoerper, KNO1 antikoerper, KS antikoerper, cb371 antikoerper, cb529 antikoerper, fc96d06 antikoerper, sb:cb529 antikoerper, wu:fb47h10 antikoerper, wu:fb77g12 antikoerper, wu:fc50f04 antikoerper, wu:fc96d06 antikoerper, wu:fk02h12 antikoerper, kno antikoerper, kno1 antikoerper, collagen type XVIII alpha 1 chain antikoerper, collagen type XVIII alpha 1 chain a antikoerper, collagen, type XVIII, alpha 1 antikoerper, collagen type XVIII alpha 1 antikoerper, COL18A1 antikoerper, col18a1a antikoerper, Col18a1 antikoerper, col18a1 antikoerper

Hintergrund:

Synonyms: KS, KNO, KNO1, Collagen alpha-1(XVIII) chain, COL18A1

Background: COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.

Gen-ID: 80781

UniProt: P39060