TUBB3 Antikörper

Produktnummer ABIN6699201

Produktdetails anti-TUBB3 Antikörper

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TUBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität (Details): Cross reactivity with tubulin beta 3 from other species has not been determined

Aufreinigung: Anti-Tubulin beta 3 Antibody is directed against rat Tubulin beta III protein. The antibody was Protein G purified. .

Immunogen:

Immunogen: Anti-Tubulin beta 3 Monoclonal Antibody was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues specific to beta III tubulin.

Immunogen Type: Peptide

Klon: AA10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:1,000

Application Note: Anti-Tubulin beta 3 (Mouse) antibody is suitable for use in Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to beta III tubulin proteins in the appropriate cell lysate or extract.

Western Blot Dilution: 1:10,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Details zu TUBB3

Target: TUBB3 (Tubulin, beta 3 (TUBB3))

Andere Bezeichnung: Tubulin beta 3 (TUBB3 Produkte)

Synonyme: CDCBM antikoerper, CFEOM3A antikoerper, TUBB4 antikoerper, beta-4 antikoerper, TUBB3 antikoerper, 3200002H15Rik antikoerper, M(beta)3 antikoerper, M(beta)6 antikoerper, tubb3 antikoerper, tubulin beta 3 class III antikoerper, tubulin, beta 3 class III antikoerper, tubulin beta 3 class III L homeolog antikoerper, beta-tubulin 3 antikoerper, tubulin beta-3 chain antikoerper, beta tubulin 3 antikoerper, TUBB3 antikoerper, Tubb3 antikoerper, tubb3 antikoerper, tubb3.L antikoerper, LOC100581245 antikoerper, tub3 antikoerper

Hintergrund:

Synonyms: mouse anti-Tubulin beta 3 Antibody, Neuron-specific class III beta-tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III

Background: Tubulin beta 3 Antibody detects Tubulin beta III protein. Tubulin is the major constituent of microtubules, existing as a heterodimer of the α and β subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.

Gene Name: TUBB3

Gen-ID: 246118

UniProt: Q4QRB4

Pathways: Microtubule Dynamics, M Phase