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tau Antikörper (Atto 594)

Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal Atto 594
Produktnummer ABIN6698761
  • Target Alle tau Antikörper anzeigen
    tau (tau Protein)
    Reaktivität
    • 525
    • 501
    • 499
    • 40
    • 28
    • 27
    • 18
    • 6
    • 3
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 630
    • 36
    • 2
    • 1
    Kaninchen
    Klonalität
    • 605
    • 63
    • 1
    Polyklonal
    Konjugat
    • 209
    • 40
    • 34
    • 33
    • 33
    • 33
    • 32
    • 32
    • 32
    • 30
    • 24
    • 24
    • 24
    • 24
    • 24
    • 13
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Dieser tau Antikörper ist konjugiert mit Atto 594
    Applikation
    • 549
    • 272
    • 263
    • 205
    • 92
    • 85
    • 68
    • 59
    • 53
    • 36
    • 34
    • 16
    • 12
    • 12
    • 12
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Detects ~45.8kda.
    Aufreinigung
    Protein A Purified
    Immunogen
    Synthetic peptide from the full length of Human Tau
    Top Product
    Discover our top product tau Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:1000 dilution of ABIN6698761 was sufficient for detection of Tau in 10 μg of human SH-SY5Y cell lysate cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    tau (tau Protein)
    Andere Bezeichnung
    Tau (tau Produkte)
    Synonyme
    DDPAC antikoerper, FTDP-17 antikoerper, MAPTL antikoerper, MSTD antikoerper, MTBT1 antikoerper, MTBT2 antikoerper, PPND antikoerper, TAU antikoerper, tau antikoerper, PHF-tau antikoerper, microtubule associated protein tau antikoerper, MAPT antikoerper
    Hintergrund
    Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). There are six isoforms of tau in the adult human brain: three with four repeat units (4R) and three with three repeat units (3R) (4). K18 is a truncated form of human tau containing only the 4 microtubule binding repeats (5). P301L (PL) is a mutation where proline is replaced by leucine at codon 301 of tau, and has been linked to frontotemporal dementia (6).
    Gen-ID
    4137
    UniProt
    P10636
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