TNFRSF18 Antikörper (C-Term) (Atto 390)

Produktnummer ABIN6698698

Produktdetails anti-TNFRSF18 Antikörper (Atto 390)

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF18 Antikörper ist konjugiert mit Atto 390

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Expressed in lymph node, peripheral blood leukocytes and weakly in spleen.,Detects 25 kDa.

Kreuzreaktivität: Human, Maus

Aufreinigung: Protein G Purified

Immunogen: Synthetic peptide from the C-terminal of Human Tumor Necrosis Factor Receptor Superfamily, Member 18

Klon: T9P4G4-D7

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

• WB (1:1000)
• optimal dilutions for assays should be determined by the user.

Kommentare:

A 1:1000 dilution of ABIN6698698 was sufficient for detection of Tumor Necrosis Factor Receptor Superfamily, Member 18 in 15 μg of Mouse Skeletal Muscle by ECL immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Conjugated antibodies should be stored at 4°C

Details zu TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Andere Bezeichnung: TNFRSF18 (TNFRSF18 Produkte)

Synonyme: GITR antikoerper, TNFRSF18 antikoerper, AITR antikoerper, Gitr antikoerper, CD357 antikoerper, GITR-D antikoerper, TNF receptor superfamily member 18 antikoerper, tumor necrosis factor receptor superfamily, member 18 antikoerper, TNFRSF18 antikoerper, Tnfrsf18 antikoerper

Hintergrund: TNFRSF18 is a member of the tumor necrosis factor receptor (TNF-R) superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25+/CD4+ regulatory T cells (1), and could be a suitable molecular target for preventing or treating automimmune diseases (2).

Gen-ID: 8784

NCBI Accession: NP_004186

Pathways: Cancer Immune Checkpoints