SLC1A5 Antikörper (AA 465-515)

Produktnummer ABIN669081

Produktdetails anti-SLC1A5 Antikörper

Target: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Bindungsspezifität: AA 465-515

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC1A5 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC1A5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SLC1A5 Antikörper (ABIN669081)

Díaz-Carballo, Klein, Acikelli, Wilk, Saka, Jastrow, Wennemuth, Dammann, Giger-Pabst, Khosrawipour, Rassow, Nienen, Strumberg: "Cytotoxic stress induces transfer of mitochondria-associated human endogenous retroviral RNA and proteins between cancer cells." in: Oncotarget, Vol. 8, Issue 56, pp. 95945-95964, (2017) (PubMed).

Huang, Zhao, Zhao, Wu, Jiang, Ma, Zhang: "Upregulated SLC1A5 promotes cell growth and survival in colorectal cancer." in: International journal of clinical and experimental pathology, Vol. 7, Issue 9, pp. 6006-14, (2014) (PubMed).

Details zu SLC1A5

Target: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Andere Bezeichnung: SLC1A5 (SLC1A5 Produkte)

Synonyme: aaat antikoerper, asct2 antikoerper, atbo antikoerper, m7v1 antikoerper, m7vs1 antikoerper, r16 antikoerper, rdrc antikoerper, AAAT antikoerper, ASCT2 antikoerper, ATBO antikoerper, M7V1 antikoerper, M7VS1 antikoerper, R16 antikoerper, RDRC antikoerper, Slc1a7 antikoerper, Asct2 antikoerper, H4-ASCT2 antikoerper, solute carrier family 1 (neutral amino acid transporter), member 5 antikoerper, solute carrier family 1 member 5 S homeolog antikoerper, solute carrier family 1 member 5 antikoerper, slc1a5 antikoerper, slc1a5.S antikoerper, SLC1A5 antikoerper, Slc1a5 antikoerper

Hintergrund:

Synonyms: R16, AAAT, ATBO, M7V1, RDRC, ASCT2, M7VS1, Neutral amino acid transporter B(0), ATB(0), Baboon M7 virus receptor, RD114/simian type D retrovirus receptor, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5, SLC1A5, RDR

Background: Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. May also be activated by insulin. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). Acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses (PubMed:10051606, PubMed:10196349).

Gen-ID: 6510

UniProt: Q15758

Pathways: Dicarboxylic Acid Transport, Warburg Effekt