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Angiotensin I Converting Enzyme 1 Antikörper (AA 801-900)

ACE Reaktivität: Human, Maus, Ratte, Hund WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN668631
  • Target Alle Angiotensin I Converting Enzyme 1 (ACE) Antikörper anzeigen
    Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
    Bindungsspezifität
    • 16
    • 15
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 801-900
    Reaktivität
    • 102
    • 53
    • 50
    • 21
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund
    Wirt
    • 89
    • 30
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 82
    • 42
    Polyklonal
    Konjugat
    • 60
    • 16
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser Angiotensin I Converting Enzyme 1 Antikörper ist unkonjugiert
    Applikation
    • 96
    • 44
    • 43
    • 31
    • 25
    • 25
    • 14
    • 9
    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Hund, Human, Maus, Ratte
    Homologie
    Cow,Sheep,Pig
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from Human ACE1
    Isotyp
    IgG
    Top Product
    Discover our top product ACE Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Jiang, Li, Lu, Wang, Yu, Sui, Fu: "Ginsenoside Rg3 induces ginsenoside Rb1-comparable cardioprotective effects independent of reducing blood pressure in spontaneously hypertensive rats." in: Experimental and therapeutic medicine, Vol. 14, Issue 5, pp. 4977-4985, (2017) (PubMed).

    Liu, Jiang, Zhang, Li, Li, Xie, Hu: "Pulmonary artery denervation improves pulmonary arterial hypertension induced right ventricular dysfunction by modulating the local renin-angiotensin-aldosterone system." in: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 192, (2016) (PubMed).

  • Target
    Angiotensin I Converting Enzyme 1 (ACE) (Angiotensin I Converting Enzyme (Peptidyl-Dipeptidase A) 1 (ACE))
    Andere Bezeichnung
    ACE (ACE Produkte)
    Synonyme
    ACE1 antikoerper, CD143 antikoerper, DCP antikoerper, DCP1 antikoerper, ICH antikoerper, MVCD3 antikoerper, AW208573 antikoerper, Dcp1 antikoerper, StsRR92 antikoerper, dcp antikoerper, ace1 antikoerper, dcp1 antikoerper, xace antikoerper, cd143 antikoerper, ACE antikoerper, angiotensin I converting enzyme antikoerper, angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 antikoerper, angiotensin-converting enzyme antikoerper, angiotensin I converting enzyme (peptidyl-dipeptidase A) 3 antikoerper, angiotensin-converting enzyme-like antikoerper, ACE antikoerper, Ace antikoerper, ace antikoerper, CpipJ_CPIJ009106 antikoerper, ACE3 antikoerper, LOC101824864 antikoerper
    Hintergrund

    Synonyms: Angiotensin Converting Enzyme 1, ACE, ACE-T, Dipeptidyl carboxy peptidase 1, Kininase II, ACE-1, testis-specic isoform precursor, ACE1, Angiotensin converting enzyme testis specic isoform, Carboxycathepsin, CD 143, DCP 1, Dipeptidyl carboxypeptidase 1, MVCD3, Peptidase P, Peptidyl dipeptidase A, Testicular ECA

    Background: Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

    Gen-ID
    1636
    UniProt
    P12821
    Pathways
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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