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NREP Antikörper (AA 25-68)

C5orf13 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN668496
  • Target Alle NREP (C5orf13) Antikörper anzeigen
    NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 25-68
    Reaktivität
    • 20
    • 11
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 20
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NREP Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human P311
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Li, Yao, He, Gao, Bai, Yang, Zhang, Zhan, Tan, Zhou, Takata, Wu, Luo: "P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor β1 expression." in: Stem cell research & therapy, Vol. 7, Issue 1, pp. 175, (2016) (PubMed).

    Yao, Li, He, Yang, Zhang, Zhan, Xu, Tan, Zhou, Wu, Luo: "P311 Accelerates Skin Wound Reepithelialization by Promoting Epidermal Stem Cell Migration Through RhoA and Rac1 Activation." in: Stem cells and development, Vol. 26, Issue 6, pp. 451-460, (2016) (PubMed).

    Yao, Yang, He, Li, Xu, Zhang, Li, Zhan, Sun, Tan, Zhou, Luo, Wu: "P311 promotes renal fibrosis via TGFβ1/Smad signaling." in: Scientific reports, Vol. 5, pp. 17032, (2015) (PubMed).

    Yan, Zhang, Wang, Xu, Ren, Zhang, Shi, Chen, Shi, Tian, Zhao, Dong: "Significant reduction of the GLUT3 level, but not GLUT1 level, was observed in the brain tissues of several scrapie experimental animals and scrapie-infected cell lines." in: Molecular neurobiology, Vol. 49, Issue 2, pp. 991-1004, (2014) (PubMed).

    Peng, Yuan, Tan, Ma, Bian, Xu, He, Cao, Huang, Cui, Gan, Wang, Zhou, Hu, Yang, Luo, Wu: "Identification of ITGB4BP as a new interaction protein of P311." in: Life sciences, Vol. 90, Issue 15-16, pp. 585-90, (2012) (PubMed).

  • Target
    NREP (C5orf13) (Chromosome 5 Open Reading Frame 13 (C5orf13))
    Andere Bezeichnung
    P311 protein (C5orf13 Produkte)
    Synonyme
    3.1 antikoerper, CZH5orf13 antikoerper, NREP antikoerper, C5orf13 antikoerper, D4S114 antikoerper, P311 antikoerper, PRO1873 antikoerper, PTZ17 antikoerper, SEZ17 antikoerper, AI325076 antikoerper, D0H4S114 antikoerper, Harp antikoerper, neuronal regeneration related protein antikoerper, NREP antikoerper, Nrep antikoerper
    Hintergrund

    Synonyms: P311, PTZ17, SEZ17, D4S114, C5orf13, PRO1873, Neuronal regeneration-related protein, Neuronal protein 3.1, Protein p311, NREP

    Background: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation.

    Gen-ID
    9315
    UniProt
    Q16612
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