TSG101 Antikörper (Tumor Susceptibility Gene 101)

Details for Product anti-TSG101 Antibody No. ABIN6674283
Antigen
Reaktivität
Human, Maus, Ratte (Rattus)
128
61
51
12
10
8
8
8
6
6
5
4
3
2
1
1
Wirt
Kaninchen
117
15
Klonalität
Polyklonal
Konjugat
Dieser TSG101 Antikörper ist unkonjugiert
8
5
4
4
4
4
3
3
3
3
3
3
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
113
62
52
20
15
14
7
3
3
3
3
2
1
1
1
Optionen
Immunogen Fusion protein of human TSG101
Isotyp IgG
Reinigung Affinity purification
Antigen
Andere Bezeichnung TSG101 (TSG101 Antibody Abstract)
Hintergrund The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008]
Synonyms: TSG10, VPS23
Gen-ID 7251
UniProt Q99816
Applikations-hinweise Recommended dilutions: WB: 1:500-1:1000, IHC: 1:50-1:100, IF: 1:20-1:50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C,-80 °C
Informationen zur Lagerung

Storage: -20 °C/-80 °C

Bilder des Herstellers
Image no. 1 for anti-Tumor Susceptibility Gene 101 (TSG101) antibody (ABIN6674283) Western blot analysis of extracts of Hela cell line, using TSG101 antibody.
Image no. 2 for anti-Tumor Susceptibility Gene 101 (TSG101) antibody (ABIN6674283) Western blot analysis of extracts of Hela cell line, using TSG101 antibody.
Produkt verwendet in: Zhao, Wu, Duan, Ma, Shen, Wei, Cui, Zhang, Xie, Liu: "Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS." in: Journal of proteome research, Vol. 13, Issue 12, pp. 5391-402, 2015 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)

Yu, Yan, Yang, Wu, Ling, Chen, Tang, Tan, Cao, Wu, Yan, Wang: "Platelets promote tumour metastasis via interaction between TLR4 and tumour cell-released high-mobility group box1 protein." in: Nature communications, Vol. 5, pp. 5256, 2014 (PubMed). Von den Autoren verwendete Methode: Western Blotting (WB)