Tamalin/GRASP Antikörper (C-Term)

Produktnummer ABIN6658234

Produktdetails anti-Tamalin/GRASP Antikörper

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Bindungsspezifität: C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tamalin/GRASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reactivity with GRASP from other species has not been determined.

Aufreinigung: Anti-GRASP Antibody is directed against rat GRASP protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Expect reactivity with the following species based on sequence homology: bovine, canine, human, rat, and mouse.

Immunogen:

Immunogen: Anti-GRASP Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-GRASP (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 95 kDa in size corresponding to GRASP protein in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Details zu Tamalin/GRASP

Target: Tamalin/GRASP (GRASP) (GRP1 (General Receptor For phosphoinositides 1)-Associated Scaffold Protein (GRASP))

Andere Bezeichnung: GRASP (GRASP Produkte)

Synonyme: GRASP antikoerper, tamalin antikoerper, TAMALIN antikoerper, general receptor for phosphoinositides 1 associated scaffold protein antikoerper, GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein antikoerper, GRASP antikoerper, grasp antikoerper, Grasp antikoerper

Hintergrund:

Synonyms: GRIP1-associated protein 1, Glutamate receptor-interacting protein 1, GRASP1

Background: GRASP Antibody detects GRASP protein. PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo. Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity. Therefore, GRASP antibody is ideal for investigators involved in neuronal plasticity and remodelling and more generally in Neuroscience.

Gene Name: GRIPAP1

Gen-ID: 116493

UniProt: P97879