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ASCL2 Antikörper (C-Term)

ASCL2 Reaktivität: Maus WB, ELISA, FM Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6657882
  • Target Alle ASCL2 Antikörper anzeigen
    ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 45
    • 32
    • 20
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 43
    • 4
    • 1
    Kaninchen
    Klonalität
    • 43
    • 5
    Polyklonal
    Konjugat
    • 24
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ASCL2 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 14
    • 13
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)
    Kreuzreaktivität (Details)
    Cross reactivity with Ash2 from other species not tested.
    Aufreinigung
    Anti-Ash2 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.
    Immunogen

    Immunogen: Anti-Ash2 Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides of mouse Ash2: two containing an amino acid sequence from the internal and one containing an amino acid sequence from the C-terminal part of the protein.

    Immunogen Type: Peptide

  • Applikationshinweise

    Application Note: Anti-Ash2 Antibody is suitable for ELISA, Immunofluorescence and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 68 kDa in the appropriate cell lysate or extract.

    ELISA Dilution: 1:100 - 1:500

    Western Blot Dilution: 1:1,000

    IF Microscopy Dilution: 1:200

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    0.01 % (w/v) Sodium Azide

    Stabilizer: None

    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    RT,4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Target
    ASCL2 (Achaete-Scute Complex Homolog 2 (ASCL2))
    Andere Bezeichnung
    Ash2 (ASCL2 Produkte)
    Synonyme
    ASH2 antikoerper, HASH2 antikoerper, MASH2 antikoerper, bHLHa45 antikoerper, ASCL2 antikoerper, 2410083I15Rik antikoerper, Mash2 antikoerper, achaete-scute family bHLH transcription factor 2 antikoerper, ASCL2 antikoerper, Ascl2 antikoerper
    Hintergrund

    Synonyms: Set1/Ash2 histone methyltransferase complex subunit ASH2, ASH2-like protein, ASH2L1, ASH2L2, Bre2

    Background: Ash2 is a component of the Set1/Ash2 histone methyltransferase (HMT) complex. This complex specifically methylates K4 of histone H3, thereby activating transcription. Methylation of K4 is blocked by premethylation of the neighboring K9, a repressor of transcription. This indicates that the Set1/Ash2 HMT complex mediates the crosstalk between K9 methylation and K4 methylation. Ash2 plays a role in hematopoiesis and may be associated with some kinds of leukemia. Anti-Ash2 Antibody is ideal for research in Gene Expression, Epigenetics, Cell Signaling and Cancer.

    Gene Name: ASH2L

    Gen-ID
    9070
    NCBI Accession
    NP_001098684
    UniProt
    Q9UBL3
    Pathways
    Stem Cell Maintenance
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