NR2C1 Antikörper (N-Term)

Produktnummer ABIN6657689

Produktdetails anti-NR2C1 Antikörper

Target: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Bindungsspezifität: N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR2C1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-TR2 antibody is directed against mouse Testicular Receptor 2 protein. Anti-TR2 antibody is provided as monospecific neat serum. Reactivity is expected against human and rat.

Immunogen:

Immunogen: Anti-TR2 Antibody was produced in rabbit by repeated immunizations with TR2 fusion protein from the N-terminal region of the Testicular Receptor 2 protein.

Immunogen Type: Recombinant Protein

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-Testicular Receptor 2 (Rabbit) antibody is suitable for use in Western Blots. Anti-Testicular Receptor 2 antibodies are specific for the ~64 kDa TR2 protein in Western blots of testes and nuclear extracts from MEL cell lines. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Details zu NR2C1

Target: NR2C1 (Nuclear Receptor Subfamily 2, Group C, Member 1 (NR2C1))

Andere Bezeichnung: Testicular Receptor 2 (TR2) (NR2C1 Produkte)

Synonyme: TR2 antikoerper, NR2C1 antikoerper, dor2 antikoerper, tr2-11 antikoerper, xDOR2 antikoerper, DKFZp468M0512 antikoerper, si:dkey-183c16.2 antikoerper, zgc:110672 antikoerper, 4831444H07Rik antikoerper, 80.3 antikoerper, Eenr antikoerper, Tr2-11 antikoerper, Tr2 antikoerper, Psg4 antikoerper, TR2-11 antikoerper, PSG9 antikoerper, nr2c1 antikoerper, nuclear receptor subfamily 2 group C member 1 antikoerper, nuclear receptor subfamily 2 group C member 1 S homeolog antikoerper, nuclear receptor subfamily 2, group C, member 1 antikoerper, pregnancy specific beta-1-glycoprotein 4 antikoerper, nuclear receptor subfamily 2 group C member 1 L homeolog antikoerper, NR2C1 antikoerper, nr2c1.S antikoerper, nr2c1 antikoerper, Nr2c1 antikoerper, PSG4 antikoerper, nr2c1.L antikoerper

Hintergrund:

Synonyms: Nuclear receptor subfamily 2 group C member 1, Orphan nuclear receptor TR2, mTR2

Background: TR2 antibody detects Testicular receptor 2 (TR2), which is a member of the orphan nuclear receptor family. It is widely expressed at a low level throughout the adult testis. TR2 represses transcription and binds DNA directly interacting with HDAC3 and HDAC4 via DNA-binding domains. TR2 has also been implicated in regulation of estrogen receptor activity in mammary glands. In addition, TR2 has recently been shown to form a heterodimer with TR4 that can bind to the direct repeat 6 element of the hepatitis B virus (HBV) enhancer II region thus suppressing HBV gene expression. Anti-TR2 Antibody is ideal for investigators involved in Cell Signaling, Neuroscience, and Stem Cell research.

Gene Name: NR2C1

Gen-ID: 22025

UniProt: Q505F1

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway