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KCNMB2 Antikörper (C-Term, N-Term)

KCNMB2 Reaktivität: Maus WB, IHC, IP Wirt: Maus Monoclonal S53-32 unconjugated
Produktnummer ABIN6657685
  • Target Alle KCNMB2 Antikörper anzeigen
    KCNMB2 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 2 (KCNMB2))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term, N-Term
    Reaktivität
    • 36
    • 20
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus
    Wirt
    • 36
    • 1
    Maus
    Klonalität
    • 36
    • 1
    Monoklonal
    Konjugat
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNMB2 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 20
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Aufreinigung
    Anti-BK channel BETA2 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with BK channel BETA2 from human, mouse, and rat based on 100% homology with the immunizing sequence. Detects endogenous and exogenous hsp22 in monomeric, dimeric and tetrameric forms in WB. Does not cross react with alpha crystallin. Cross-reactivity with BK channel BETA2 from other sources has not been determined. Ion Channels research.
    Immunogen

    Immunogen: BK channel BETA2 Antibody was produced in mice by repeated immunizations with a fusion protein N-terminus and C-terminus regions of mouse BKBeta2.

    Immunogen Type: Recombinant Protein

    Klon
    S53-32
    Isotyp
    IgG1
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  • Applikationshinweise

    Immunohistochemistry Dilution: User Optimized

    Application Note: Anti-BK channel Beta3 Antibody is suitable for use in WB, IP, and IHC. Specific conditions for reactivity should be optimized by the end user.

    Immunoprecipitation Dilution: User Optimized

    Western Blot Dilution: 1:2000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 50 % (v/v) Glycerol

    Lagerung
    RT,4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Target
    KCNMB2 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 2 (KCNMB2))
    Andere Bezeichnung
    BK channel BETA2 (KCNMB2 Produkte)
    Synonyme
    KCNMB3 antikoerper, zgc:101842 antikoerper, KCNMB2 antikoerper, 2700049B16Rik antikoerper, 3110031N04Rik antikoerper, Kcmb2 antikoerper, potassium calcium-activated channel subfamily M regulatory beta subunit 2 antikoerper, potassium large conductance calcium-activated channel, subfamily M, beta member 2 antikoerper, KCNMB2 antikoerper, kcnmb2 antikoerper, Kcnmb2 antikoerper
    Hintergrund

    Synonyms: KCNMB2, Calcium-activated potassium channel subunit beta-2, BK channel subunit beta-2, BKbeta2, Calcium-activated potassium channel, subfamily M subunit beta-2, Charybdotoxin receptor subunit beta-2, K(VCA)beta-2, Maxi K channel subunit beta-2, Slo-beta-2

    Background: BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release. A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological diseases. Findings suggest that the distribution of the beta subunits in the brain can modulate the BK channels to contribute to the pathophysiology of epilepsy and dyskinesia. This has major implications on other physiological processes in tissues other than the brain.

    Gene Name: Kcnmb2

    Gen-ID
    72413
    NCBI Accession
    NP_082507
    UniProt
    Q9CZM9
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