Retinoid X Receptor gamma Antikörper

Produktnummer ABIN6657359

Produktdetails anti-Retinoid X Receptor gamma Antikörper

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Retinoid X Receptor gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reactivity to other sources has not been tested.

Aufreinigung: Anti-Retinoic Acid Receptor gamma antibody detects Retinoic Acid Receptor gamma. Retinoic Acid Receptor gamma antibody was Protein G purified. This antibody is directed against human retinoic acid receptor gamma protein. Reactivity is expected from the following species based on 100% sequence homology: bovine, mouse, non-human primate and rat.

Immunogen:

Immunogen: Anti-Retinoic Acid Receptor gamma was produced by repeated immunizations with a synthetic peptide corresponding to amino acid residues from the hinged region of RAR-gamma.

Immunogen Type: Peptide

Klon: 1373

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-Retinoid X Receptor gamma antibody is suitable for use in Western Blotting to detect a single band at approximately 48 kDa corresponding to the RXR-γ isotype in the appropriate cell lysate or extract. Researchers should determine optimal titers for applications that are not stated below.

Western Blot Dilution: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Details zu Retinoid X Receptor gamma

Target: Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))

Andere Bezeichnung: Retinoid X Receptor gamma (RXRG Produkte)

Synonyme: NR2B3 antikoerper, RXRC antikoerper, zgc:92183 antikoerper, RXRgamma antikoerper, RXRG antikoerper, RXR-gamma antikoerper, nr2b3 antikoerper, xrxrg antikoerper, rxrc antikoerper, Nr2b3 antikoerper, NR2B1 antikoerper, RXR antikoerper, rxra antikoerper, rxrg antikoerper, retinoid X receptor gamma antikoerper, retinoid X receptor, gamma b antikoerper, retinoid X receptor gamma L homeolog antikoerper, retinoid x receptor, gamma a antikoerper, RXRG antikoerper, rxrgb antikoerper, rxrg.L antikoerper, rxrg antikoerper, Rxrg antikoerper, RXRGAMMA antikoerper, rxrga antikoerper

Hintergrund:

Synonyms: mouse anti-Retinoid X Receptor gamma Antibody, mouse anti-RXRG antibody, Nuclear receptor subfamily 2 group B member 3, Retinoid X receptor gamma

Background: Retinoic acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXRα, β and γ) preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.

Gene Name: RXRG

Gen-ID: 6258

UniProt: P48443

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway