Telefon:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antikoerper-online.de

LY86 Antikörper (Internal Region)

LY86 Reaktivität: Human ELISA, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6656262
$449.00
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
Lieferung in 1 bis 2 Werktagen
  • Target Alle LY86 Antikörper anzeigen
    LY86 (Lymphocyte Antigen 86 (LY86))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 38
    • 27
    • 22
    Human
    Wirt
    • 50
    • 9
    • 3
    Kaninchen
    Klonalität
    • 51
    • 11
    Polyklonal
    Konjugat
    • 26
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LY86 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 21
    • 13
    • 13
    • 12
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus, Ratte (Rattus)
    Kreuzreaktivität (Details)
    Cross reactivity with MD-1 from other sources has not been determined.
    Aufreinigung
    Anti-MD-1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography.
    Immunogen

    Immunogen: Anti-MD-1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 15 amino acid synthetic peptide from near the internal region of human MD-1.

    Immunogen Type: Peptide

    Isotyp
    IgG
  • Applikationshinweise

    Immunohistochemistry Dilution: 2.5 μg/mL

    Application Note: Anti-MD-1 Antibody has been tested for use in ELISA, Western Blotting, and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 18 kDa in Western Blots of specific cell lysates and tissues.

    ELISA Dilution: 1:10,000-1:20,000

    Western Blot Dilution: 1-2 μg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    RT,4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Target
    LY86 (Lymphocyte Antigen 86 (LY86))
    Andere Bezeichnung
    MD-1 (LY86 Produkte)
    Synonyme
    MD-1 antikoerper, MMD-1 antikoerper, dJ80N2.1 antikoerper, MD1 antikoerper, LY86 antikoerper, lymphocyte antigen 86 antikoerper, LY86 antikoerper, Ly86 antikoerper
    Hintergrund

    Synonyms: MD-1 Antibody, MD-1, MMD-1, dJ80N2.1, MD1, Lymphocyte antigen 86, Protein MD-1, Ly-86

    Background: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

    Gene Name: LY86

    Gen-ID
    9450
    NCBI Accession
    NP_004262
    UniProt
    O95711
    Pathways
    Toll-Like Receptors Cascades
Sie sind hier:
Kundenservice