ZBTB8A Antikörper (C-Term)

Produktnummer ABIN6656009

Produktdetails anti-ZBTB8A Antikörper

Target: ZBTB8A (Zinc Finger and BTB Domain Containing 8A (ZBTB8A))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB8A Antikörper ist unkonjugiert

Applikation: ELISA, Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)

Kreuzreaktivität: Human, Maus

Aufreinigung: Anti-ZBTB8 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. At least two isoforms of ZBTB8 are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.

Immunogen:

Immunogen: Anti-ZBTB8 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid synthetic peptide near the C-terminus of human ZBTB8.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 2.5 μg/mL

Application Note: Anti-ZBTB8 Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 50 kDa in Western Blots of specific cell lysates and tissues.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu ZBTB8A

Target: ZBTB8A (Zinc Finger and BTB Domain Containing 8A (ZBTB8A))

Andere Bezeichnung: ZBTB8 (ZBTB8A Produkte)

Synonyme: BOZF1 antikoerper, ZBTB8 antikoerper, ZNF916A antikoerper, 2410081M15Rik antikoerper, AI480941 antikoerper, Zbtb8 antikoerper, zinc finger and BTB domain containing 8A antikoerper, zinc finger and BTB domain containing 8a antikoerper, ZBTB8A antikoerper, Zbtb8a antikoerper

Hintergrund:

Synonyms: ZBTB8 Antibody, BOZF1, ZBTB8, ZNF916A, BOZF1, Zinc finger and BTB domain-containing protein 8A, BOZ-F1

Background: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB8, also known as BOZ-F1, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB8, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB8 may act as a transcriptional repressor or be involved in tumorigenesis.

Gene Name: ZBTB8A

Gen-ID: 79842

UniProt: Q9H5J0