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TLR9 Antikörper (C-Term)

TLR9 Reaktivität: Human ELISA, FM, IHC, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6655851
$411.00
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
Lieferung in 1 bis 2 Werktagen
  • Target Alle TLR9 Antikörper anzeigen
    TLR9 (Toll-Like Receptor 9 (TLR9))
    Bindungsspezifität
    • 19
    • 17
    • 9
    • 8
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 115
    • 50
    • 18
    • 7
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 75
    • 40
    • 10
    • 8
    • 1
    • 1
    Kaninchen
    Klonalität
    • 86
    • 49
    Polyklonal
    Konjugat
    • 77
    • 16
    • 15
    • 8
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TLR9 Antikörper ist unkonjugiert
    Applikation
    • 95
    • 59
    • 56
    • 55
    • 25
    • 17
    • 16
    • 11
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)
    Kreuzreaktivität
    Human, Maus
    Kreuzreaktivität (Details)
    Cross reactivity with TLR9 from other sources has not been determined.
    Aufreinigung
    Anti-TLR9 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography.
    Immunogen

    Immunogen: Anti-TLR9 antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to 16 amino acids near the C-terminus of human TLR9.

    Immunogen Type: Peptide

    Isotyp
    IgG
  • Applikationshinweise

    Immunohistochemistry Dilution: 2 μg/mL

    Application Note: Anti-TLR9 Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 116 kDa in Western Blots of specific cell lysates and tissues.

    ELISA Dilution: 0.5-2 μg/mL

    Western Blot Dilution: 0.5-2 μg/mL

    IF Microscopy Dilution: 10 μg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    RT,4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Target
    TLR9 (Toll-Like Receptor 9 (TLR9))
    Andere Bezeichnung
    TLR9 (TLR9 Produkte)
    Synonyme
    CD289, toll like receptor 9, toll-like receptor 9, TLR9, Tlr9
    Hintergrund

    Synonyms: TLR9 Antibody, CD289, Toll-like receptor 9

    Background: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. TLR9 forms a subfamily along with TLR7 and TLR8 that recognize viral RNA and CpG DNA sequences and are localized in intracellular acidic compartments such as the phagolysosome. Unlike other TLRs which act through adaptor molecules such as TOLLIP, TIRAP, TRIF, and MyD88 to activate various kinases and transcription factors to respond to potential infection, TLR9 is strictly dependent on MyD88.

    Gene Name: TLR9

    Gen-ID
    7099
    NCBI Accession
    NP_612564
    UniProt
    O00206
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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