CD11c Antikörper (APC)

Produktnummer ABIN6655425

Produktdetails anti-CD11c Antikörper (APC)

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD11c Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Kreuzreaktivität (Details): Cross reactivity with CD11c from other sources has not been tested

Aufreinigung: Allophycocyanin conjugated CD11c Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD11c. Reactivity is observed against human CD11c, Baboon, Chimpanzee, Cynomolgus, and Rhesus. . Anti-CD11c is conjugated with APC under optimal conditions and the solution is free of unconjugated APC.

Immunogen:

Immunogen: Anti-CD11c Antibody (Monoclonal) was produced by repeated immunizations with CD11c antigen.

Klon: 3-9

Isotyp: IgG1

Labeling Ratio: 1-2

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-CD11c is useful for Flow Cytometry, Immunofluorescence, and Immunoprecipitation. Researchers should determine optimal titers for applications that are not stated.

Immunoprecipitation Dilution: User Optimized

Flow Cytometry Dilution: 5μL/test/1x10e5 to 1x10e8 cells

IF Microscopy Dilution: User Optimized

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.1 % Gelatin

0.09 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Dilute only prior to immediate use. This product is stable at 4° C as an undiluted liquid. Use subdued lighting during handling and incubation of cells prior to analysis. Store reagent in the dark. DO NOT FREEZE.

Details zu CD11c

Target: CD11c (ITGAX) (Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

Andere Bezeichnung: CD11c (ITGAX Produkte)

Synonyme: CD11C antikoerper, SLEB6 antikoerper, RGD1561123 antikoerper, AI449405 antikoerper, Cd11c antikoerper, Cr4 antikoerper, N418 antikoerper, integrin subunit alpha X antikoerper, integrin alpha X antikoerper, ITGAX antikoerper, Itgax antikoerper

Hintergrund:

Synonyms: Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150 95, CD11c

Background: The 3.9 antibody is widely used as a marker for CD11c expression on dendritic cells (DC), often in parallel with markers for CD11b, for identification of developmental stages and mature subsets of this cell type. CD11c is prominently expressed on tissue macrophages, and is also detected on activated neutrophils, granulocytes, some types of activated T cells and intestinal intraepithelial lymphocytes (IEL).L killing through its interactions with fibrinogen, CD54, and iC3b.

Gene Name: ITGAX

Gen-ID: 3687

NCBI Accession: NP_000878

UniProt: P20702

Pathways: Komplementsystem, Activated T Cell Proliferation, Integrin Complex