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SLC7A11 Antikörper

SLC7A11 Reaktivität: Human WB, ELISA, IHC, FACS, IP, FM Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6655336
  • Target Alle SLC7A11 Antikörper anzeigen
    SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))
    Reaktivität
    • 35
    • 15
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 1
    Kaninchen
    Klonalität
    • 39
    • 3
    Polyklonal
    Konjugat
    • 21
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLC7A11 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Fluorescence Microscopy (FM)
    Aufreinigung
    This affinity purified antibody is directed against human xCT. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human and orangutan, and 88% identity to mouse.
    Immunogen

    Immunogen: Anti-xCT antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human xCT conjugated to Keyhole Limpet Hemocyanin (KLH).

    Immunogen Type: Peptide

    Isotyp
    IgG
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  • Applikationshinweise

    Immunohistochemistry Dilution: 1:200

    Application Note: Anti-xCT Antibody has been tested in Western Blot, ELISA, Immunofluorescence and Flow cytometry. Expect a band at 55.4 kDa in western blot using appropriate lysates. Positive control used NIH-3T3, Hela, HCT-116, A549, or PC3 whole cell lysates at 0.1-1.0 μg/mL for WB and PC3 with MeOH at 10 μg/mL in IF. Although not tested, this antibody is likely functional in immunohistochemistry and immunoprecipitation.

    Immunoprecipitation Dilution: User Optimized

    ELISA Dilution: 5.0 μg/mL

    Flow Cytometry Dilution: 1:200

    Western Blot Dilution: 1:1000

    IF Microscopy Dilution: 10 μg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    0.01 % (w/v) Sodium Azide

    Stabilizer: None

    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    RT,4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Target
    SLC7A11 (Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11 (SLC7A11))
    Andere Bezeichnung
    xCT (SLC7A11 Produkte)
    Synonyme
    SLC7A11 antikoerper, DKFZp468E122 antikoerper, CCBR1 antikoerper, xCT antikoerper, 9930009M05Rik antikoerper, AI451155 antikoerper, sut antikoerper, solute carrier family 7 member 11 antikoerper, solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 antikoerper, solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 antikoerper, SLC7A11 antikoerper, Slc7a11 antikoerper
    Hintergrund

    Synonyms: rabbit anti-xCT antibody, SLC7A11, Cystine/glutamate transporter, Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, Solute carrier family 7 member 11

    Background: xCT belongs to the amino acid-polyamine-organocation (APC) superfamily and L-type amino acid transporter (LAT) family. xCT gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. Increased expression of this gene results in neuronal cell death. xCT may be associated with kaposi sarcoma, dyscalculia, cystinuria, spondylolsis, and anemia of prematurity. Anti-xCT Antibody is useful for researchers interested in Cancer Research, Glucose/Energy Metabolism Research, and Cell Surface Protein Interaction Research.

    Gene Name: SLC7A11

    Gen-ID
    23657
    NCBI Accession
    NP_055146
    UniProt
    Q9UPY5
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