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PDGFRB Antikörper (AA 911-992)

PDGFRB Reaktivität: Human, Maus, Ratte ELISA, IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6654145
$562.38
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 2 bis 3 Werktagen
  • Target Alle PDGFRB Antikörper anzeigen
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Bindungsspezifität
    • 22
    • 21
    • 21
    • 16
    • 15
    • 11
    • 9
    • 9
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 911-992
    Reaktivität
    • 213
    • 92
    • 83
    • 5
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 193
    • 29
    • 3
    • 2
    Kaninchen
    Klonalität
    • 183
    • 44
    Polyklonal
    Konjugat
    • 115
    • 14
    • 9
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Dieser PDGFRB Antikörper ist unkonjugiert
    Applikation
    • 123
    • 84
    • 58
    • 54
    • 53
    • 30
    • 30
    • 17
    • 16
    • 11
    • 9
    • 4
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Aufreinigung
    Antigen affinity purified
    Immunogen
    Human PDGFRB recombinant protein (amino acids E911-L992) was used as the immunogen for the PDGFRB antibody.
    Isotyp
    IgG
  • Applikationshinweise
    Optimal dilution of the PDGFRB antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the PDGFRB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    Andere Bezeichnung
    Platelet Derived Growth Factor Receptor beta / PDGFRB (PDGFRB Produkte)
    Synonyme
    AI528809, CD140b, PDGFR-1, Pdgfr, CD140B, IBGC4, JTK12, PDGFR, PDGFR1, platelet derived growth factor receptor, beta polypeptide, platelet derived growth factor receptor beta, Pdgfrb, PDGFRB
    Hintergrund
    Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene. The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia.
    UniProt
    P09619
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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