TRPV1 Antikörper (N-Term)

Produktnummer ABIN657909

Produktdetails anti-TRPV1 Antikörper

Target: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Bindungsspezifität: AA 124-153, N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPV1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRPV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-153 amino acids from the N-terminal region of human TRPV1.

Klon: RB33721

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000. WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TRPV1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Referenzen für anti-TRPV1 Antikörper (ABIN657909)

Miyano, Minami, Yokoyama, Ohbuchi, Yamaguchi, Murakami, Shiraishi, Yamamoto, Matoba, Uezono: "Tramadol and its metabolite m1 selectively suppress transient receptor potential ankyrin 1 activity, but not transient receptor potential vanilloid 1 activity." in: Anesthesia and analgesia, Vol. 120, Issue 4, pp. 790-8, (2015) (PubMed).

Details zu TRPV1

Target: TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))

Andere Bezeichnung: TRPV1 (TRPV1 Produkte)

Synonyme: si:dkey-9e15.2 antikoerper, VR.5'sv antikoerper, Vr1 antikoerper, Vr1l1 antikoerper, VR1 antikoerper, OTRPC1 antikoerper, TRPV1alpha antikoerper, TRPV1beta antikoerper, VR-1 antikoerper, transient receptor potential cation channel, subfamily V, member 1 antikoerper, transient receptor potential cation channel subfamily V member 1 antikoerper, trpv1 antikoerper, Trpv1 antikoerper, TRPV1 antikoerper

Hintergrund: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.

Molekulargewicht: 94956

Gen-ID: 7442

NCBI Accession: NP_061197, NP_542435, NP_542436, NP_542437

UniProt: Q8NER1

Pathways: Dicarboxylic Acid Transport