Osteoprotegerin Antikörper (AA 243-271)

Produktnummer ABIN657660

Produktdetails anti-Osteoprotegerin Antikörper

Target: Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))

Bindungsspezifität: AA 243-271

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Osteoprotegerin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNFRSF11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human TNFRSF11B.

Klon: RB33719

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TNFRSF11B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu Osteoprotegerin

Target: Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))

Andere Bezeichnung: TNFRSF11B (TNFRSF11B Produkte)

Synonyme: CD254 antikoerper, ODF antikoerper, OPGL antikoerper, OPTB2 antikoerper, RANKL antikoerper, TRANCE antikoerper, hRANKL2 antikoerper, sOdf antikoerper, OCIF antikoerper, OPG antikoerper, TR1 antikoerper, Opg antikoerper, ocif antikoerper, opg antikoerper, tr1 antikoerper, TNF superfamily member 11 antikoerper, TNF receptor superfamily member 11b antikoerper, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antikoerper, TNF receptor superfamily member 11B antikoerper, tumor necrosis factor receptor superfamily member 11b S homeolog antikoerper, tumor necrosis factor receptor superfamily, member 11b antikoerper, TNFSF11 antikoerper, TNFRSF11B antikoerper, Tnfrsf11b antikoerper, tnfrsf11b.S antikoerper

Substanzklasse: Chemical

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Molekulargewicht: 46026

Gen-ID: 4982

NCBI Accession: NP_002537

UniProt: O00300