PHOX2B Antikörper (Paired-Like Homeobox 2b)

Details for Product anti-PHOX2B Antibody No. ABIN6572005
Antigen
  • phox2
  • xphox2b
  • phox2b
  • PHOX2B
  • pmx2b
  • nbphox
  • NBLST2
  • NBPhox
  • PMX2B
  • Dilp1
  • Pmx2b
  • paired-like homeobox 2b
  • paired like homeobox 2b S homeolog
  • paired-like homeobox 2bb
  • paired like homeobox 2b
  • phox2b
  • phox2b.S
  • phox2bb
  • PHOX2B
  • Phox2b
Reaktivität
Human, Maus, Ratte (Rattus)
38
36
9
2
2
2
2
2
2
1
1
1
1
Wirt
Kaninchen
42
9
2
1
Klonalität
Polyklonal
Konjugat
Dieser PHOX2B Antikörper ist unkonjugiert
3
3
3
3
3
3
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
44
35
7
4
4
2
2
Optionen
Immunogen Recombinant protein of human PHOX2B
Isotyp IgG
Reinigung Affinity purification
Plasmids, Primers & others Plasmide, Primers & weitere PHOX2B products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung PHOX2B (PHOX2B Antibody Abstract)
Hintergrund

Synonyms: NBLST2,NBPhox,Neuroblastoma paired type homeobox protein,Neuroblastoma Phox,Paired like homeobox 2b,Paired mesoderm homeobox 2b,Paired mesoderm homeobox protein 2B,Paired-like homeobox 2B,PHOX 2B,PHOX 2B homeodomain protein,PHOX2B,PHOX2B homeodomain protein,PHX2B,PMX 2B,PMX2B

Background: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.

Molekulargewicht

Observed_MW: 32kDa

Calculated_MW: 31kDa

Gen-ID 8929
UniProt Q99453
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder des Herstellers
Image no. 1 for anti-Paired-Like Homeobox 2b (PHOX2B) antibody (ABIN6572005) Western blot analysis of extracts of various cell lines, using PHOX2B antibody.
Image no. 2 for anti-Paired-Like Homeobox 2b (PHOX2B) antibody (ABIN6572005) Immunohistochemistry of paraffin-embedded rat liver using PHOX2B antibody.
Image no. 3 for anti-Paired-Like Homeobox 2b (PHOX2B) antibody (ABIN6572005) Immunohistochemistry of paraffin-embedded rat kidney using PHOX2B antibody.
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