FBXO22 Antikörper

Produktnummer ABIN6571705

Produktdetails anti-FBXO22 Antikörper

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human FBXO22

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FBXO22

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Andere Bezeichnung: FBXO22 (FBXO22 Produkte)

Synonyme: FBXO22 antikoerper, DKFZp469L0535 antikoerper, fbxo22 antikoerper, MGC146708 antikoerper, si:busm1-132m23.3 antikoerper, FBX22 antikoerper, FISTC1 antikoerper, 0610033L19Rik antikoerper, 1600016C16Rik antikoerper, F-box protein 22 antikoerper, FBXO22 antikoerper, fbxo22 antikoerper, Fbxo22 antikoerper

Hintergrund:

Synonyms: 0610033L19Rik,1600016C16Rik,F box only protein 22,F box protein 22,F box protein FBX22p44 ,F-box only protein 22,F-box protein FBX22p44,FBX22,FBX22,FBXO 22,FBXO22,FIST domain containing 1,FISTC1,FLJ13986,MGC124731,MGC31799

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and, as a transcriptional target of the tumor protein p53, is thought to be involved in degradation of specific proteins in response to p53 induction. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 45kDa

Calculated_MW: 4kDa/30kDa/44kDa

Gen-ID: 26263

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development