C8orf4 Antikörper
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- Target Alle C8orf4 Antikörper anzeigen
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser C8orf4 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human C8orf4 (NP_064515.1).
- Isotyp
- IgG
- Top Product
- Discover our top product C8orf4 Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- C8orf4 (Chromosome 8 Open Reading Frame 4 (C8orf4))
- Andere Bezeichnung
- C8orf4 (C8orf4 Produkte)
- Synonyme
- TC-1 antikoerper, TC1 antikoerper, 1110065B09Rik antikoerper, AW121743 antikoerper, AW321058 antikoerper, C8ORF4 antikoerper, transcriptional and immune response regulator antikoerper, chromosome 22 open reading frame, human C8orf4 antikoerper, TCIM antikoerper, C22H8ORF4 antikoerper, Tcim antikoerper
- Hintergrund
- This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
- Molekulargewicht
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Observed_MW: Refer to figures
Calculated_MW: 12kDa
- Gen-ID
- 56892
- UniProt
- Q9NR00
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