COMT Antikörper

Produktnummer ABIN6570281

Produktdetails anti-COMT Antikörper

Target: COMT (Catechol-O-Methyltransferase (COMT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COMT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human COMT (NP_009294.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu COMT

Target: COMT (Catechol-O-Methyltransferase (COMT))

Andere Bezeichnung: COMT (COMT Produkte)

Synonyme: Comt1 antikoerper, D16Wsu103e antikoerper, D330014B15Rik antikoerper, COMT antikoerper, mb-comt antikoerper, s-comt antikoerper, comt antikoerper, MGC154444 antikoerper, zgc:114157 antikoerper, si:dkey-13a21.15 antikoerper, zK13A21.15 antikoerper, zgc:162236 antikoerper, catechol-O-methyltransferase antikoerper, microRNA 4761 antikoerper, catechol-O-methyltransferase S homeolog antikoerper, methyltransferase antikoerper, catechol-o-methyltransferase antikoerper, catechol-O-methyltransferase a antikoerper, catechol-O-methyltransferase b antikoerper, catechol O-methyltransferase antikoerper, COMT antikoerper, Comt antikoerper, MIR4761 antikoerper, comt antikoerper, comt.2 antikoerper, comt.S antikoerper, Rv1703c antikoerper, Mb1729c antikoerper, comta antikoerper, comtb antikoerper, LOC100354142 antikoerper

Hintergrund: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

Molekulargewicht:

Observed_MW: 28kDa, 32kDa

Calculated_MW: 24kDa/30kDa

Gen-ID: 1312

UniProt: P21964

Pathways: Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interaktom