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KCNN3 Antikörper

KCNN3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6570256
  • Target Alle KCNN3 Antikörper anzeigen
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    Reaktivität
    • 25
    • 17
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 24
    • 1
    Kaninchen
    Klonalität
    • 25
    Polyklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KCNN3 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 8
    • 7
    • 6
    • 3
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human KCNN3 (NP_740752.1).
    Isotyp
    IgG
    Top Product
    Discover our top product KCNN3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
    Andere Bezeichnung
    KCNN3 (KCNN3 Produkte)
    Synonyme
    KCa2.3 antikoerper, SK3 antikoerper, SKCA3 antikoerper, hSK3 antikoerper, potassium calcium-activated channel subfamily N member 3 antikoerper, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 antikoerper, Kcnn3 antikoerper, KCNN3 antikoerper
    Hintergrund
    Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: 50-85kDa

    Calculated_MW: 47kDa/48kDa/82kDa

    Gen-ID
    3782
    UniProt
    Q9UGI6
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