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SUB1 Antikörper

SUB1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6570210
  • Target Alle SUB1 Antikörper anzeigen
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    Reaktivität
    • 35
    • 13
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 33
    • 2
    Kaninchen
    Klonalität
    • 34
    • 1
    Polyklonal
    Konjugat
    • 24
    • 3
    • 3
    • 3
    • 1
    • 1
    Dieser SUB1 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 18
    • 15
    • 8
    • 6
    • 4
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide of human PABPC4 (NP_003810.1).
    Isotyp
    IgG
    Top Product
    Discover our top product SUB1 Primärantikörper
  • Applikationshinweise
    IHC 1:50-1:200 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
    Andere Bezeichnung
    PC4 (SUB1 Produkte)
    Synonyme
    P15 antikoerper, PC4 antikoerper, p14 antikoerper, AI842364 antikoerper, P9 antikoerper, Pc4 antikoerper, Rpo2tc1 antikoerper, SUB1 homolog, transcriptional regulator antikoerper, SUB1 homolog (S. cerevisiae) antikoerper, SUB1 antikoerper, Sub1 antikoerper
    Hintergrund
    Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht

    Observed_MW: 79kDa

    Calculated_MW: 69kDa/70kDa/72kDa

    Gen-ID
    8761
    UniProt
    Q13310
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